Protein Info for MPMX26_00027 in Acinetobacter radioresistens SK82

Annotation: Putative aliphatic sulfonates-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF04069: OpuAC" amino acids 41 to 258 (218 residues), 51.1 bits, see alignment E=3e-17 PF13379: NMT1_2" amino acids 41 to 258 (218 residues), 52.1 bits, see alignment E=1.8e-17 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 43 to 323 (281 residues), 273.6 bits, see alignment E=8.9e-86 PF09084: NMT1" amino acids 51 to 260 (210 residues), 72.1 bits, see alignment E=1.3e-23

Best Hits

Swiss-Prot: 44% identical to SSUA_ECOLI: Putative aliphatic sulfonates-binding protein (ssuA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 69% identity to aci:ACIAD0037)

MetaCyc: 44% identical to aliphatic sulfonate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-56-RXN [EC: 7.6.2.14]

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (329 amino acids)

>MPMX26_00027 Putative aliphatic sulfonates-binding protein (Acinetobacter radioresistens SK82)
MYSLKVFLISSFIALGLSGCQKTSSDTAPGQQSVQENKLKTLAIGYQKSSLNLLVARQQQ
LFEQQFPGVQVAWKEFPAGPQMLEALAVGAIDFGAVGNTPPVFAQAAGKDLKYIGYEVVP
QNAQALLIPADSSIRTLADLKGKRIAVQKGSSAHELLAKVLQKAGLSWQDIQPIWLPPAD
ARAAFDKQSIDAWSIWEPYLSAAELDAKAKVLIDGQAFARTYSFYIANPQFIEQHPGATE
KILQSLNTADQWVLQHQQQALKIYQQSTGLKQNIAQRVIDKRLKPSPIYSLKPEVVQAQQ
EIADLFQQVKLIPKSIQVSQVVWVPTPKN