Protein Info for MPMX19_06858 in Azospirillum sp. SherDot2

Annotation: Acetophenone carboxylase gamma subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 PF05378: Hydant_A_N" amino acids 11 to 186 (176 residues), 134.5 bits, see alignment E=5e-43 PF01968: Hydantoinase_A" amino acids 210 to 494 (285 residues), 256.4 bits, see alignment E=5.2e-80 PF19278: Hydant_A_C" amino acids 513 to 682 (170 residues), 45.2 bits, see alignment E=1.1e-15

Best Hits

KEGG orthology group: K01473, N-methylhydantoinase A [EC: 3.5.2.14] (inferred from 90% identity to azl:AZL_c03130)

Predicted SEED Role

"N-methylhydantoinase A (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>MPMX19_06858 Acetophenone carboxylase gamma subunit (Azospirillum sp. SherDot2)
MDGGLGEADWKVGVDIGGTFIDFCALDTRSGRVASLKVLTTPDDPGAELMTGLTLLAERE
GLDPRAVTRFVHGTTVGMNTVIQRKGAPLALLTNAGFEDVIELARLRMPDTYSLFCSRPD
QLIARDMVFGIPARLRSDGTERQAPDMAAVADAVAAVKAKGAMGVVVSFLHSWRDDAHET
AVKEEVARLAPELFVFTSAEVWPVIREYERTTTAVLNAYVHPRISGYLSALEGRLAGRGV
PARPLLTKSNGGVMNAAEGKRACVHMLLSGAASGVNGAAWLARQAGEPRILTLDIGGTSA
DFALIVDGQAQFGVGEMIGEFPLHIPSVSVSSIGIGGGSIASVDGQGVLRVGPESAGSTP
GPACYGRGGEWATVTDAMVVCGWLGHSQMAYGQLRMDAGLARAAVKRLADELFRSVEATA
QAILDVAVSEMFAEVEKMAARAGVDVRDFALMPFGGGGPMLGVFLARELGMPRVVAPRWP
GVVSALGGLVADLRGDFVRTLFADLSPGLMPALREAFAAMGREGRDWLAAQGHTGAAELR
VVADMRYAGQSYEIETALNPEWLDGSDPDAIADAFHAAHTRLYDFHDPDGRIEIVNLRLS
AIGNGPALHFPTAPEEPHAASAERSVPVFTGGAVTPVGLYRRADLQAGARFEGPAIVAQE
DTTFAIPAGTAARVDAHLNLHLTFAE