Protein Info for MPMX19_06857 in Azospirillum sp. SherDot2

Annotation: Monomeric sarcosine oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01266: DAO
  • amino acids 2 to 348 (347 residues), 231.4 bits, E=4.6e-72
• PF00890: FAD_binding_2
  • amino acids 3 to 46 (44 residues), 24.5 bits, 3e-09
• PF13450: NAD_binding_8
  • amino acids 5 to 43 (39 residues), 28 bits, 4.5e-10

Best Hits

KEGG orthology group: K00303, sarcosine oxidase, subunit beta [EC: 1.5.3.1] (inferred from 89% identity to azl:AZL_c03140)

Predicted SEED Role

"Sarcosine oxidase beta subunit (EC 1.5.3.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.5.3.1)

MetaCyc Pathways

• glycine betaine degradation I (6/8 steps found)
• creatinine degradation I (2/4 steps found)
• creatinine degradation II (2/5 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.5.3.1

Use Curated BLAST to search for 1.5.3.1

Protein Sequence (387 amino acids)

>MPMX19_06857 Monomeric sarcosine oxidase (Azospirillum sp. SherDot2)
MRVIVLGGGLIGSAAAFFLARRGLSVTLLERNRVGTGATVASFGNIRRTGRYLPQLPLAH
RSRALWGEAERLLGRDVEFRATGHLRLVFDEDGLADMRRYIADARPWGLDLDELSPPEIR
RRFPGLGPGAIAASFSPQDGSGNPRLIAPAFTDAARRLGAEIVEECGPVEVSATASGFEA
ATHRGRFTADRLLNAAGAWGATIAARFGESVPMAAYGPQMGVTEPLPHRILPVVGMWSRA
GGDGYLRQVERGNIVFGGGAERVPVALDPGHARADPARLPGQLRALVRLLPALADVTVIR
TWSGCEGYVADKLPVMGASATTPGLFHAFGFSGHGFQLGPGVGDVMAEIIATGHSETPLH
DFRIGRFQAAAPQTAAAQAAAAHAPQA