Protein Info for MPMX19_06830 in Azospirillum sp. SherDot2

Annotation: Maleate isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02990: ectoine utilization protein EutA
  • amino acids 16 to 253 (238 residues), 405.4 bits, E=3.8e-126
• PF17645: Amdase
  • amino acids 80 to 250 (171 residues), 86.8 bits, E=1.8e-28

Best Hits

KEGG orthology group: K01799, maleate isomerase [EC: 5.2.1.1] (inferred from 69% identity to mlo:mlr7137)

Predicted SEED Role

"Arylmalonate decarboxylase (EC 4.1.1.76)" (EC 4.1.1.76)

MetaCyc Pathways

• nicotinate degradation II (1/5 steps found)
• nicotinate degradation I (1/6 steps found)
• picolinate degradation (1/7 steps found)
• nicotine degradation III (VPP pathway) (3/10 steps found)
• nicotine degradation II (pyrrolidine pathway) (3/11 steps found)
• superpathway of nicotinate degradation (1/18 steps found)

KEGG Metabolic Maps

• Butanoate metabolism
• Nicotinate and nicotinamide metabolism

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.1

Use Curated BLAST to search for 4.1.1.76 or 5.2.1.1

Protein Sequence (261 amino acids)

>MPMX19_06830 Maleate isomerase (Azospirillum sp. SherDot2)
MPSLPILRSPTALDFDDRPVEKRVGLVVLATDHTTEPDFRRMVASDRIGIYTARIAYANP
TTPENLRRMQPRLAEGAALILPDEPLAAICYSCTSASVVMGDDAIEQAIASAKPGVPVIT
PPAAARHGLTAFGAQRIAVLTPYTEQTSRPMAAYFGVHGFDIARFTCFGLDDDREMARIA
PASLVRAAVEAMPPDADALFISCTALRSAGVAAEIEDAIGRPVVTSNQATAWATLRLCGD
DRPRPEGGRLMTLPLPQDAWS