Protein Info for MPMX19_06631 in Azospirillum sp. SherDot2

Annotation: Hemolysin secretion protein D, plasmid

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 61 to 82 (22 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 59 to 471 (413 residues), 321 bits, see alignment E=6.4e-100 PF13533: Biotin_lipoyl_2" amino acids 101 to 145 (45 residues), 32.7 bits, see alignment 1e-11 PF00529: CusB_dom_1" amino acids 128 to 415 (288 residues), 27.8 bits, see alignment E=3.9e-10 PF13437: HlyD_3" amino acids 320 to 409 (90 residues), 46.3 bits, see alignment E=1.3e-15

Best Hits

KEGG orthology group: None (inferred from 59% identity to azl:AZL_f01580)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (472 amino acids)

>MPMX19_06631 Hemolysin secretion protein D, plasmid (Azospirillum sp. SherDot2)
MTAQKLAKIETARVPANDVASRAPASPLDKRAKARGKAAVGAFQKDTEAIQNAPDPFLAR
VTLHLLGLFVIGVITWASMSYLDKIVASQGKIISTEPNVMVQPLEMAAIKQVLVRAGDVV
HQGQVLATLDPTFTQADVLQLESRLANADAQIARLEAEHDGKPLVPVTDRYGYGTLQQAL
WRERQAQYQSQMQNYEEKLARLQSNVSKYEMDRLHLNERLKVVREIENMRSSLLATQVGS
KLNLLQAVSDRIDIERNLVLNQNELQGNRHDLQAQLAERDVFIQQWNGKIIEELATQSNE
REALREQLTKARKRQALVQLDAPVDAIVLEVSPKATPGSIAKEAEPLFTLVPVGAPLEVE
ANIDARDLAFVQIGDKVRVKLDAYPYMQHGSLEGEVATISEDSFSNKDNAGGMLFYRARI
RLLTTTLDNVPSNFRLIPGMPLVADIKVGERRIITYFLRPILRGFDESLREP