Protein Info for MPMX19_06618 in Azospirillum sp. SherDot2

Annotation: Glucose-1-phosphate cytidylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details TIGR02623: glucose-1-phosphate cytidylyltransferase" amino acids 1 to 256 (256 residues), 449.5 bits, see alignment E=1.6e-139 PF00483: NTP_transferase" amino acids 2 to 201 (200 residues), 61.6 bits, see alignment E=9.1e-21 PF12804: NTP_transf_3" amino acids 3 to 56 (54 residues), 31.6 bits, see alignment E=1.8e-11

Best Hits

Swiss-Prot: 65% identical to RFBF_SALTI: Glucose-1-phosphate cytidylyltransferase (rfbF) from Salmonella typhi

KEGG orthology group: K00978, glucose-1-phosphate cytidylyltransferase [EC: 2.7.7.33] (inferred from 77% identity to oca:OCAR_4619)

MetaCyc: 64% identical to glucose-1-phosphate cytidylyltransferase (Yersinia enterocolitica (type O:8))
Glucose-1-phosphate cytidylyltransferase. [EC: 2.7.7.33]

Predicted SEED Role

"Glucose-1-phosphate cytidylyltransferase (EC 2.7.7.33)" in subsystem dTDP-rhamnose synthesis (EC 2.7.7.33)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.33

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>MPMX19_06618 Glucose-1-phosphate cytidylyltransferase (Azospirillum sp. SherDot2)
MKAVILAGGLGTRISEETTSRPKPMIEIGGRPILWHIMKIYSANGINDFIVCLGYKGYFI
KEYFANYFLHMSDVTFDMRNNGMEIHQNNAEPWRVTLIDTGEDTMIGGRIKRILPYVRDD
EAFCVTYGDGVGNVDIRQVIDLHKREGRLATVTAMQPPGRFGSIRYDGARVVAFEEKPLG
DGGWINGGFFVLSPNVGSYIEGDSSVWEREPLERLAQDNQLSVHFHRGFWQPMDTLRDKR
YLEELWDTGKAPWKVW