Protein Info for MPMX19_06450 in Azospirillum sp. SherDot2

Annotation: Fe(2+) transporter FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 701 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 230 to 253 (24 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 368 to 393 (26 residues), see Phobius details amino acids 404 to 428 (25 residues), see Phobius details amino acids 466 to 486 (21 residues), see Phobius details amino acids 524 to 530 (7 residues), see Phobius details amino acids 532 to 549 (18 residues), see Phobius details amino acids 567 to 591 (25 residues), see Phobius details amino acids 601 to 623 (23 residues), see Phobius details amino acids 638 to 662 (25 residues), see Phobius details PF02421: FeoB_N" amino acids 11 to 170 (160 residues), 184.1 bits, see alignment E=2.6e-58 PF01926: MMR_HSR1" amino acids 11 to 127 (117 residues), 66.6 bits, see alignment E=4.2e-22 TIGR00437: ferrous iron transport protein B" amino acids 218 to 595 (378 residues), 317.4 bits, see alignment E=1e-98 PF07670: Gate" amino acids 297 to 391 (95 residues), 82.4 bits, see alignment E=5.9e-27 amino acids 468 to 598 (131 residues), 56.7 bits, see alignment E=5.9e-19 PF07664: FeoB_C" amino acids 410 to 462 (53 residues), 64 bits, see alignment 1.7e-21

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 72% identity to rce:RC1_2448)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (701 amino acids)

>MPMX19_06450 Fe(2+) transporter FeoB (Azospirillum sp. SherDot2)
MPNAIIAAPLVALVGNPNCGKTALFNALTGSRQKVANYPGVTVERKEGRCVGRAGRRLRV
LDLPGTYSLRARSPDEEVTRDVVLGRRDGEAVPDILVCVVDATNLRLNLRLVLELKRVGR
PVILALNMMDMAERRGCSIDLGALSTALDMPVVPMVAVRGDGVQDLIDRIDRVVDSDVSA
GLEKGAVGWTEPSSQDLRAYHRAVEAILAQAVRTPSSPHTVTRRIDAVLLQPVLGLGVLL
LILFLMFQAVFAWAKLPMDLIDAGLSWTKDAVASGMPAGPLNSLLTDGVIAGVGSVVIFL
PQILVLFLFIQVLEDSGYMARAAFLLDRLMGGVGLHGRAFIPLLSSFACAVPGIMATRTI
ENRADRLATIMIAPLMTCSARLPVYALLIAAFVPDRPVFGGMIGLPGLVMFILYAAGILA
ALLVAFILKRTLFQGAREPLLMELPAYRLPRPSNIALGLAERAKTFLTRAGTTIFLLMVV
IWFLASYPGAPEGATGPAIQHSFAGMIGHALEPALAPIGFNWQIAIALVPGMAAREVAVG
VLGTVYALSATGDALRVTLGDTLATSWSLPTALSLLAWYVFAPQCLSTLSVVRRETNSRF
WPAAMFTYMLVFAYAASFVTYRLTSAIIAERSAVGFGFVWQSVIVVPLGAGALAWTLWRY
LLPVKVRALMHRSVIGDDLPASGCGGCGNCGASTKPGTGCH