Protein Info for MPMX19_06415 in Azospirillum sp. SherDot2

Annotation: Copper resistance protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR01480: copper-resistance protein, CopA family" amino acids 24 to 617 (594 residues), 699.6 bits, see alignment E=1.7e-214 PF07732: Cu-oxidase_3" amino acids 46 to 158 (113 residues), 127 bits, see alignment E=8e-41 amino acids 507 to 621 (115 residues), 38.8 bits, see alignment E=1.8e-13 PF07731: Cu-oxidase_2" amino acids 67 to 158 (92 residues), 28 bits, see alignment E=3.2e-10 amino acids 502 to 619 (118 residues), 105.4 bits, see alignment E=4.2e-34 PF00394: Cu-oxidase" amino acids 236 to 340 (105 residues), 74.9 bits, see alignment E=1.6e-24

Best Hits

KEGG orthology group: None (inferred from 51% identity to acb:A1S_2936)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (624 amino acids)

>MPMX19_06415 Copper resistance protein A (Azospirillum sp. SherDot2)
MDRTSNFFTRRDALKLAAMAGMAGVVTAYPGRHSFAAADQTLDLAVERTRITVDGVTSNA
IAIGGSIPAPTLRLREGQEVVIRVTNRLNEPTSIHWHGLLLQGVMDGAPGFNGFVPIRPG
ETYTYHFKLRQAGTYWYHSHSAGQEQEGMYGAIVIEPAERDPVRADREYVVLLSDHTIES
PNSVLRNLKVSEGYYNNKKRTLVDFFRDAQRDGWSTTVRDRLDWAEMRMDATDLADVTGY
HFLVNGKGAKDNWTAIYKPGERVRLRIINGSAMTIFDVRIPGLPMTVVAADGQNVAPVKV
DEFRFGVGETYDVIVLPQGDKPFTFFAEPIDRTGYARATLAVRDGLEGEIPERRPRAILT
MADMGMSHEGMDHGAMAGMDHSKMAGMGAGAMPGMDHSNMPGMDHSKMAGMGAGAMPGMD
HSNMPGMDHSKMAGMGAGAMPGMDHSNMPGMNNGSMEGMAKAAASSNDQAMGWADAGTPP
GAKALSYADLKSLTKAKDVREPTHEIEVRLSGMMSRYIWTLNGNKFDEGEPIRVGYGDRV
RIRFVNETMMAHPMHLHGMFMELENGQAGRLPRKHVVLVPPGKTVSVQLTADEPGEWPFH
CHLLYHMASGMMTRFIVERRSASL