Protein Info for MPMX19_06350 in Azospirillum sp. SherDot2

Annotation: Arsenical-resistance protein Acr3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 55 to 75 (21 residues), see Phobius details amino acids 93 to 116 (24 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 192 to 211 (20 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 287 to 341 (55 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 15 to 343 (329 residues), 380.8 bits, see alignment E=3.1e-118 PF01758: SBF" amino acids 61 to 256 (196 residues), 106 bits, see alignment E=1e-34

Best Hits

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 97% identity to azl:AZL_027590)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (357 amino acids)

>MPMX19_06350 Arsenical-resistance protein Acr3 (Azospirillum sp. SherDot2)
MTADIHAAPAARPAMGLFERYLSVWVALCIVAGIALGHLVPGVFQAIAAAEVAKVNLPVA
VLIWLMIVPMLLKIDLGALGQVKEHWRGVGVTLFINWAVKPFSMALLGTLFIGNLFAPLL
PQDQISSYIAGLILLAAAPCTAMVFVWSNLCEGEPHYTLSQVALNDIIMVFAFAPLVGLL
LGVASITVPWDTLLLSVLLYIVIPVVAAQLWRRSLLATGGEAALKRTLDLIQPVSLVALL
TTLVLLFGFQGEQILAQPLVILLLAVPILIQVYFNAGLAYWLSRRFGVAWCVAAPAALIG
ASNFFELAVAAAISLFGLGSGAALATVVGVLVEVPVMLSVVKIVKATKPWYEGRTHA