Protein Info for MPMX19_06278 in Azospirillum sp. SherDot2

Annotation: S-sulfocysteine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00291: PALP
  • amino acids 42 to 291 (250 residues), 127.7 bits, E=3e-41

Best Hits

KEGG orthology group: K01738, cysteine synthase A [EC: 2.5.1.47] (inferred from 51% identity to oan:Oant_0655)

Predicted SEED Role

"Cysteine synthase (EC 2.5.1.47)" in subsystem Cysteine Biosynthesis or Methionine Biosynthesis (EC 2.5.1.47)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• L-cysteine biosynthesis I (2/2 steps found)
• seleno-amino acid biosynthesis (plants) (2/5 steps found)
• superpathway of seleno-compound metabolism (7/19 steps found)

KEGG Metabolic Maps

• Cysteine metabolism
• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.47

Use Curated BLAST to search for 2.5.1.47

Protein Sequence (361 amino acids)

>MPMX19_06278 S-sulfocysteine synthase (Azospirillum sp. SherDot2)
MSLEMTMSQPQSRESRGFPDYELPRLVRLTDNLHGAAFFLMKLLPARHMLDRAAADGRLK
PGGTICETTSGTFGLALAMLAAVRGYKLILVSDPAIDEHLHKRLLELGVTLEIVEKPYEI
GGFQTARLDRLRAALEANPGSFCPSQYGNADNPRAYAEVAEQIAERLGHVDCLVGTVGSG
GSMSGIARFLRHLNPDLHVIGVDTPNSVVFGQPDGKRLLRGLGNSLVPPNVDHRQFDEVH
WVGAAEAFLATRHLHQHHALYQGGTSGAAYLVADWWARTHPDRKVVTLFPDEGHRYVASI
YNDDWLAALPGWTGVLPEAPQPVAHPSDVRPSWSSFRWDRRTLDEVLAAGTPVARDLAEA
A