Protein Info for MPMX19_06177 in Azospirillum sp. SherDot2

Annotation: Cytochrome bo(3) ubiquinol oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 transmembrane" amino acids 43 to 64 (22 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 151 to 176 (26 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details TIGR02842: cytochrome o ubiquinol oxidase, subunit III" amino acids 40 to 218 (179 residues), 263.7 bits, see alignment E=5.8e-83 PF00510: COX3" amino acids 40 to 216 (177 residues), 52.9 bits, see alignment E=2.6e-18

Best Hits

Swiss-Prot: 58% identical to CYOC_SHIFL: Cytochrome bo(3) ubiquinol oxidase subunit 3 (cyoC) from Shigella flexneri

KEGG orthology group: K02299, cytochrome o ubiquinol oxidase subunit III [EC: 1.10.3.-] (inferred from 95% identity to azl:AZL_e01310)

MetaCyc: 58% identical to cytochrome bo3 subunit 3 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (219 amino acids)

>MPMX19_06177 Cytochrome bo(3) ubiquinol oxidase subunit 3 (Azospirillum sp. SherDot2)
MTTTVEAMHGGHAGHDTPRGATPPVFHVTDEHAHEGASTALGFWIYLMSDCLIFAVLFAT
YGVLGTSYAAGPTPKELFDLKLVALNTSMLLFSSITYGFAMLAMEKGRTAQTQGWLAITL
LFGLAFLGIELFEFAHMIHEGAGPWRSAFLSSFFTLVGTHGLHVTFGSVWLVTLMVQVAR
RGLIPANRRRLMCLSMFWHFLDVIWIGVFTFVYLMGALR