Protein Info for MPMX19_06100 in Azospirillum sp. SherDot2

Annotation: Electron transfer flavoprotein-ubiquinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 PF00890: FAD_binding_2" amino acids 12 to 55 (44 residues), 20.4 bits, see alignment 9.4e-08 PF13450: NAD_binding_8" amino acids 15 to 60 (46 residues), 29.3 bits, see alignment 3e-10 PF21162: ETFQO_UQ-bd" amino acids 212 to 305 (94 residues), 143.6 bits, see alignment E=8.1e-46 PF05187: Fer4_ETF_QO" amino acids 443 to 545 (103 residues), 176.7 bits, see alignment E=3.8e-56

Best Hits

Swiss-Prot: 58% identical to ETFQO_ARATH: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFQO) from Arabidopsis thaliana

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 94% identity to azl:AZL_e02150)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (549 amino acids)

>MPMX19_06100 Electron transfer flavoprotein-ubiquinone oxidoreductase (Azospirillum sp. SherDot2)
MEREPREVMEYDVLIVGAGPSGLSAAIRLRQRAVETGQELSVCVIEKGSEVGAHLLSGAV
FEPHALDELIPDWKEKGAPLTTKAREDHFLFLTETKAYKSPFAPPQMNNHGNYIISLGNL
ARWMATQAEELGVEIYPGFAAAEVLYDDKGAVKGVATGDMGIDKDGEKTGNYTPGMELHA
KQTIFAEGCRGSLTKTLFERFDLRRDCQPQTYGIGIKELWEVDPSQSKPGLIVHTIGWPM
DPKTYGGSWLYHMEGNLVSVGFVVGLDYWNPHMSPFEEFQRYKTHPAIRPTFEGGRRLSY
GARALSEGGFQSIPKLTFPGGLLIGDGAGFLNVPKIKGNHTAMKSGMVAAEAVFDHLTGG
ADNGPEVIAYPERLKQSWVWPELYAVRNIRPGFQKGLWAGLANAAYETGLKGKSPWTLKH
HADHTTLVKASEAPKIAYPKPDGKVSFDRLSSVYLSNTNHEEDQPPHLTLKDKSVPISVN
LALYDAPEQRYCPAGVYEIVRNDDGSDPRLQINAQNCVHCKTCDIKDPTQNINWVVPEGG
GGPNYPGGM