Protein Info for MPMX19_06072 in Azospirillum sp. SherDot2

Annotation: Flavohemoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF00042: Globin" amino acids 28 to 130 (103 residues), 56.7 bits, see alignment E=5.2e-19 PF00970: FAD_binding_6" amino acids 158 to 252 (95 residues), 45.8 bits, see alignment E=9.6e-16 PF00175: NAD_binding_1" amino acids 263 to 366 (104 residues), 38.4 bits, see alignment E=2.6e-13

Best Hits

Swiss-Prot: 53% identical to HMP_PSEAE: Flavohemoprotein (hmp) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K05916, nitric oxide dioxygenase [EC: 1.14.12.17] (inferred from 91% identity to azl:AZL_e03980)

Predicted SEED Role

"Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)" in subsystem Bacterial hemoglobins or Flavohaemoglobin or Glutaredoxins (EC 1.14.12.17)

Isozymes

Compare fitness of predicted isozymes for: 1.14.12.17

Use Curated BLAST to search for 1.14.12.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>MPMX19_06072 Flavohemoprotein (Azospirillum sp. SherDot2)
MLTPAQIAVIKATAPVVAANANKITGTFYPLMFERFPEVRAVFNQSHQRSSAQPEALANA
IIAYASNIDRLEVLGPAVDGIVQKHVSLNITPDQYKIVGTCLMEAIGKVLGDAVTAEVAD
AWGAAYWQLAELLIAAEEKEYARKAALTGGWRGARRFRIAEKTPESAVITSFRLAPVDGG
KVMGFHPGQYLGLRLTIDGETVHRNYSLSASPNGKDYRISVKREQQGLVSGFLHDRVQVG
DEIDVYPPAGEFVLREGAGPLLLITGGVGQTPALPLAEQALAAGRKVIYVHAALNGSVHA
FRRQVDQLASLHDALKPVYCYADPQPGDEPHMVGLLDQERLGKLLPQEPGVAAYVVGPKP
FMAAVVKALTALGLPESAIVHEFFGPREALA