Protein Info for MPMX19_05978 in Azospirillum sp. SherDot2

Annotation: C4-dicarboxylate transport transcriptional regulatory protein DctD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 PF00072: Response_reg" amino acids 10 to 119 (110 residues), 88.8 bits, see alignment E=7.1e-29 PF00158: Sigma54_activat" amino acids 148 to 315 (168 residues), 215.2 bits, see alignment E=1.2e-67 PF14532: Sigma54_activ_2" amino acids 149 to 320 (172 residues), 70.9 bits, see alignment E=3.2e-23 PF07728: AAA_5" amino acids 172 to 287 (116 residues), 30.1 bits, see alignment E=1.1e-10 PF02954: HTH_8" amino acids 410 to 448 (39 residues), 39.3 bits, see alignment 1.1e-13

Best Hits

Swiss-Prot: 54% identical to DCTD_RHILE: C4-dicarboxylate transport transcriptional regulatory protein DctD (dctD) from Rhizobium leguminosarum

KEGG orthology group: K10126, two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD (inferred from 92% identity to azl:AZL_e02970)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>MPMX19_05978 C4-dicarboxylate transport transcriptional regulatory protein DctD (Azospirillum sp. SherDot2)
MKTDPLATPVLFIDDELAMRVSVTQWLQLAGFAAQGFETPQLALDLLSPDFPGVLVTDVR
MPRMDGMAVLERALERDADLPVILVTGHGDVALAVEAMRRGAYDFIEKPFEPDHLVAVLR
RAVEKRRLVLENRGLRRRAAGGGIEARLIGTSPAIAELQRDLIDLAATSASVLIHGETGT
GKELVARCLHDFGSRGEKGAFVAVNCGAIPDSMAESELFGHEPGAFTGATQRRAGKLEHS
SGGTLFLDEIESMPLAIQVKLLRALQERTIERLGSNKQVAVDLRLVAATKIDLLDLSEAG
GFRADLYYRLNVAELHIPPLRARAEDIPLLFDYFTAEFAARHSREPRPLEPADFDALLAH
DWPGNVRELRNLAERHVLSVGRSSVAGLLRRRPVGGEAAAPPRALADQVDAFEKRAIEQA
LERCKGDIKAVMDLLDIPRRTLNEKMARHGLDRTRFLPRG