Protein Info for MPMX19_05770 in Azospirillum sp. SherDot2

Annotation: 1,2-phenylacetyl-CoA epoxidase, subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 TIGR02156: phenylacetate-CoA oxygenase, PaaG subunit" amino acids 32 to 320 (289 residues), 543.2 bits, see alignment E=6e-168 PF05138: PaaA_PaaC" amino acids 42 to 316 (275 residues), 332 bits, see alignment E=1.2e-103

Best Hits

Swiss-Prot: 71% identical to PAAA_ECOLI: 1,2-phenylacetyl-CoA epoxidase, subunit A (paaA) from Escherichia coli (strain K12)

KEGG orthology group: K02609, phenylacetic acid degradation protein (inferred from 92% identity to azl:AZL_d01620)

MetaCyc: 71% identical to phenylacetyl-CoA 1,2-epoxidase, monooxygenase subunit (Escherichia coli K-12 substr. MG1655)
RXN0-2042 [EC: 1.14.13.149]

Predicted SEED Role

"Phenylacetate-CoA oxygenase, PaaG subunit"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.149

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>MPMX19_05770 1,2-phenylacetyl-CoA epoxidase, subunit A (Azospirillum sp. SherDot2)
MYTQGLDAKTEQGAQPSPRLVTEQEAALQGRFQERVDAEEKIEPRDWMPEGYRRTLVRQI
SQHAHSEIVGMLPEGNWVTRAPTLRRKVALLAKVQDEGGHGLYLYSAAETLGVSRDELVG
QLLAGKAKYSSIFNYPTPTWADIGAIGWLVDGAAIMNQVPLCRCSYGPYARAMVRICREE
SFHQRQGYELMLALAQGTVEQKRMAQDALNRWWWPSLMMFGPSDDQSAHSAQNMAWKIKR
FSNDELRQRFVDATVPQAEFLGLTIPDPELRLNAETGHYEFGAIDWTEFNEILKGNGPCN
RERIEARRKAWDEGAWVREAAVAHAAKRQQRALKKAG