Protein Info for MPMX19_05710 in Azospirillum sp. SherDot2

Annotation: Uric acid transporter UacT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 83 to 100 (18 residues), see Phobius details amino acids 107 to 128 (22 residues), see Phobius details amino acids 136 to 157 (22 residues), see Phobius details amino acids 172 to 189 (18 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 245 to 268 (24 residues), see Phobius details amino acids 322 to 341 (20 residues), see Phobius details amino acids 347 to 371 (25 residues), see Phobius details amino acids 383 to 400 (18 residues), see Phobius details amino acids 410 to 432 (23 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 20 to 429 (410 residues), 389.3 bits, see alignment E=2.2e-120 PF00860: Xan_ur_permease" amino acids 22 to 396 (375 residues), 352.1 bits, see alignment E=1.7e-109 TIGR03173: xanthine permease" amino acids 24 to 433 (410 residues), 545 bits, see alignment E=1e-167

Best Hits

Swiss-Prot: 60% identical to UACT_ECOLI: Uric acid transporter UacT (uacT) from Escherichia coli (strain K12)

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 94% identity to azl:AZL_d02140)

MetaCyc: 60% identical to urate:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN0-530

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>MPMX19_05710 Uric acid transporter UacT (Azospirillum sp. SherDot2)
MKSAATPDVHPVDEVLAPWRLLALGLQHVLVMYAGAIAVPLIVGGALKLPKDQIAMLINA
DLFACGVVTLIQAVGVWRFGIRLPVMMGVTFAAVGPMVAMATNPSLGLLGIYGAVIGSGI
FAILAAPLVGRLLPLFPPVVTGSVIAIIGVSLMRVGVGWAGGGVGNPRFGDPAFLGIAAF
VLLTILALMKHGRGFVRNVAVLLGLVAGMVLAMVLGMVDFKGLGEAPWVALVQPFQFGMP
VFDPVAILTMSLVMIVVMIESTGMFLAVGDMVGRPVSREDLVRGLRTDGLGTLIGGVFNT
FPYTSFSQNVGLVGVTGVRSRWVCAAGGLILLLLGLLPKLAHVVASVPAFVLGGAGLVMF
GMVAATGVKILTQVDFAGRRENLIVVAVSIGVGLIPLVSDKFFSQMPAFLSPLLHSGILL
GTLTAVALNWYFNGLASADRARHDVAAAAQGAEA