Protein Info for MPMX19_05617 in Azospirillum sp. SherDot2

Annotation: Guanine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02967: guanine deaminase
  • amino acids 35 to 438 (404 residues), 549.1 bits, E=3.1e-169
• PF01979: Amidohydro_1
  • amino acids 76 to 439 (364 residues), 174.2 bits, E=4.6e-55
• PF07969: Amidohydro_3
  • amino acids 323 to 438 (116 residues), 39.5 bits, E=5.2e-14

Best Hits

KEGG orthology group: K01487, guanine deaminase [EC: 3.5.4.3] (inferred from 94% identity to azl:AZL_d02660)

Predicted SEED Role

"Guanine deaminase (EC 3.5.4.3)" in subsystem Purine Utilization or Purine conversions (EC 3.5.4.3)

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (11/11 steps found)
• guanosine nucleotides degradation III (4/4 steps found)
• guanosine nucleotides degradation II (3/4 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• drosopterin and aurodrosopterin biosynthesis (4/7 steps found)
• superpathway of guanosine nucleotides degradation (plants) (3/6 steps found)
• purine nucleotides degradation I (plants) (7/12 steps found)
• superpathway of purines degradation in plants (9/18 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.3

Protein Sequence (448 amino acids)

>MPMX19_05617 Guanine deaminase (Azospirillum sp. SherDot2)
MPDQSIAAPVSAAIRGRLLSFHRAPAGPGDMDCLTYREDGLLLVGADGRILETGDWDDLR
GRVPDGVAVDDHSGKLVLPGFIDTHIHFPQTQVIASYGAQLLDWLEKYTFIEEQRFADPA
HAAANASFFMDELLRNGTTTAVVYGSAHPQSVDALFAEAEARGAGLIAGKVMMDRHAPAA
LTDTADSSYRDGKDLIGRWHGTGRQRYAVTPRFAITSTEAQLEAAGALLREHPGVHMQTH
LSENTDEIAEVRRLFPGARDYTDVYDRFGLLGPTSLFGHCIHLSDAEMSRLSESGSVAVF
CPTSNLFIGSGLFDLDALSKPERPVRTAIATDVGGGTSYSMLRTAAEAYKVLQLRRQNLP
ALAALHWMTRGNAEALGMAGEIGSLEPGRWADLVVLDPAATPAMRHRMKAVDGDLEEELF
IQVTLGDDRSVAATYLRGRNSHLRQTGA