Protein Info for MPMX19_05253 in Azospirillum sp. SherDot2

Annotation: Carbon monoxide dehydrogenase large chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 796 PF01315: Ald_Xan_dh_C" amino acids 21 to 141 (121 residues), 106.2 bits, see alignment E=1.8e-34 PF02738: MoCoBD_1" amino acids 157 to 406 (250 residues), 265.8 bits, see alignment E=4.3e-83 PF20256: MoCoBD_2" amino acids 435 to 723 (289 residues), 315.5 bits, see alignment E=5.6e-98

Best Hits

KEGG orthology group: None (inferred from 98% identity to azl:AZL_c02260)

Predicted SEED Role

"Carbon monoxide dehydrogenase large chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (796 amino acids)

>MPMX19_05253 Carbon monoxide dehydrogenase large chain (Azospirillum sp. SherDot2)
MANPNGIGASVRRREDQRFLTGRGNYTDDFKRLNMTHAVHVRSPYAHARILGIDFTDAAA
MPGVVAVLTGADMEADKVGSLPCGWQIHSKDGSPMKEPPHYPLARDRVRYVGDAVAVVIA
ETREQARDAAEMVVVDYEELPAVGSSTRAVAGGAPLVHDDAPDNVCYDWHLGDNAAVDAA
FATAAHVAKIDLVNQRLVPNAMEPRAAMGEYDQSNGEYTLTTTSQNPHVTRLLMGAFVLG
IPEHKLRVVAPDVGGGFGSKIFHYGEEAVVTWAARKVGRPVKWTADRSESFLTDAHGRDH
VSHAELAMDADGNFLALRVSTLANLGAYLSTFAPSIPTYLYATLLAGQYKTPAIYAEVKA
VFTNTSPVDAYRGAGRPEACYLIERLVDVAAGVMGMDKTEIRRRNFVPKEAMPYQTPVAL
QYDTGDFAKNLDIALPLVDYPSFQQRRAESKARGKLRGIGFATYIEACGIAPSNVAGALG
ARAGLYECAEVRFHPTGSVTVFTGAHSHGQGHETTFAQIVAERFGIPIENVEIVHGDTNK
IPFGMGTYGSRSLAVGGSALVKAMDKVERKAKKIAAHMLEAAETDIEVKEGRFTVAGTDK
SLGIGDIALQAYVPHNFPLDELEPGLDEQAFYDPKNFTYPNGCHVCELEIDPDTGVTTIV
SFAAVDDFGNVINPLIVEGQVHGGLVQGIGQALYENCVYDEESGQLVTGSYMDYCMPRAD
DVPSFTVRYHEDQPCTHNPLGVKGCGEAGTIGAAAAVMNAVVDALSDYGVTHMDMPATPE
KVWRTIRDAAPAMAAE