Protein Info for MPMX19_05202 in Azospirillum sp. SherDot2

Annotation: Tryptophan synthase beta chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K01733, threonine synthase [EC: 4.2.3.1] (inferred from 94% identity to azl:AZL_b02460)

Predicted SEED Role

"Threonine synthase (EC 4.2.3.1)" in subsystem Threonine and Homoserine Biosynthesis (EC 4.2.3.1)

MetaCyc Pathways

aspartate superpathway (23/25 steps found)
superpathway of L-isoleucine biosynthesis I (13/13 steps found)
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
superpathway of L-threonine biosynthesis (6/6 steps found)
superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (12/15 steps found)
L-threonine biosynthesis (2/2 steps found)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.3.1

Use Curated BLAST to search for 4.2.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>MPMX19_05202 Tryptophan synthase beta chain (Azospirillum sp. SherDot2)
MAFQDINPVRFDSNLTVERPTFVTHLECAYTGERYEADTVHNLSRAGKPLLVRYDLNGVK
QTLTKSSLSERPQDLWRYRELLPVRKVEDIVSLGEAVTPLVPLPRLAKRLGAAELLVKDE
GRLPTGSFKARGLVMAVSMAKAFNIKHMAMPTNGNAGAALAAYATRAGIRTTIFCPADTP
EVNVSEIELQGATVYRVNGLIDDCGKIVGEGKAKVGWFDVSTLKEPYRIEGKKTMGLELA
EQLGWEVPDVIFYPTGGGTGLIGMWKAFAELEAIGFIGAKRPRMVAVQAAGCAPMVRAWE
QGEEHAPRWEDAHTIASGIRVPQAVGDFLILRAVRESGGFAIAVPDDAIQAALNEVAREE
GFLLCPEGAATYAAYKQALADGRVGKEERAVLFNCATGLKYPLPPVHRTLDRTRPIDYSL
FQDSGR