Protein Info for MPMX19_05169 in Azospirillum sp. SherDot2

Annotation: Vitamin B12-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01497: Peripla_BP_2" amino acids 56 to 299 (244 residues), 87.3 bits, see alignment E=5.3e-29

Best Hits

KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 83% identity to azl:AZL_004830)

Predicted SEED Role

"ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (328 amino acids)

>MPMX19_05169 Vitamin B12-binding protein (Azospirillum sp. SherDot2)
MRRFLRGVPPFTPVFAMALALQAGGALAQSYPVEVANCFETARFAAAPKRLMVHDTNMTQ
TMLDLGLAGRLVAVSGIEGVEHRLIAPPGVVAALPRLPDRSPTLEAVLSVNPDFLFAGWS
YGFNEARGLTPARLAEMGVATYTLRESCIRIGPREPIGMDTLYADLLALGAIFGVTERAE
AMVADFRRRVAAVTERVGGAADRPRVMYCDQCHTDAAPLSVGREGMTSLLMELAGGRNIF
DDIPDSYVRVSWEEMVRRDPQWIIVSAHRIPAEDTIHHMTSAPQLADVEAVRKRQFIVLT
YAEQTPSSRNVEALERMARTLHPERFTP