Protein Info for MPMX19_05108 in Azospirillum sp. SherDot2

Annotation: Glycine betaine-binding protein YehZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF04069: OpuAC" amino acids 31 to 304 (274 residues), 174.9 bits, see alignment E=1.2e-55

Best Hits

Swiss-Prot: 59% identical to YEHZ_ECOLI: Glycine betaine-binding protein YehZ (yehZ) from Escherichia coli (strain K12)

KEGG orthology group: K05845, osmoprotectant transport system substrate-binding protein (inferred from 89% identity to azl:AZL_a10040)

MetaCyc: 59% identical to glycine betaine ABC transporter periplasmic binding protein OsmF (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-283

Predicted SEED Role

"Osmoprotectant ABC transporter binding protein YehZ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>MPMX19_05108 Glycine betaine-binding protein YehZ (Azospirillum sp. SherDot2)
MFTIFNKSRAYMGAAILAVGLVAGTAQAADAVRVGSKLDAESGLLGTMILQVLQAGGIPT
ENKIQLGPTKIVRGALLSGEIDIYPEYTGNGAFFFNVDSDPVWKNAGAGYDKVRQLDQEK
NSIVWLKPAPANNTWALAVRRDVADANKLKTMEDFAKWVGGGGKAKVAASAEFVESPAAL
PSFQQTYGFALKPDQMLILAGGDTAATIRAAAEQTSGVNTAMVYGTDGAIAALDLVVLAD
TKGAQMVYEPAPTVRAAVLTANPKIADLLNPVFASLDAETLRGLNAKISVDGRDQKQVAT
DYLKSKGFLK