Protein Info for MPMX19_05105 in Azospirillum sp. SherDot2

Annotation: Glycine betaine uptake system permease protein YehW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details transmembrane" amino acids 62 to 83 (22 residues), see Phobius details amino acids 104 to 121 (18 residues), see Phobius details amino acids 125 to 138 (14 residues), see Phobius details amino acids 174 to 200 (27 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details PF00528: BPD_transp_1" amino acids 78 to 243 (166 residues), 86.9 bits, see alignment E=7.4e-29

Best Hits

Swiss-Prot: 60% identical to YEHW_ECOLI: Glycine betaine uptake system permease protein YehW (yehW) from Escherichia coli (strain K12)

KEGG orthology group: K05846, osmoprotectant transport system permease protein (inferred from 95% identity to azl:AZL_a10070)

MetaCyc: 60% identical to glycine betaine ABC transporter membrane subunit YehW (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-283

Predicted SEED Role

"Osmoprotectant ABC transporter inner membrane protein YehW"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>MPMX19_05105 Glycine betaine uptake system permease protein YehW (Azospirillum sp. SherDot2)
MTGAGMAPRDFLTDRLMLGLVVLVALVLGMPSLKPLFATLFPRLDRPLYEAESFVSLTLD
HMALVGASSLAAILLGGGAGIAVTRPWGREFRGLLETVATMGQTFPPVAVLALAVPVMGF
GPEPALIALTLYALLPVVENTVAGLDGVSAPVLDSARGLGMGPAEVLFRVELPLAAPVIL
AGIRTAVIINVGTAAIASTVGAKTLGLPIIVGLNGSNQAYVIQGALIVAALAVVIDAGFD
RLAGWLTRWSQR