Protein Info for MPMX19_05074 in Azospirillum sp. SherDot2

Annotation: L-cystine-binding protein TcyA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00497: SBP_bac_3" amino acids 36 to 252 (217 residues), 151.5 bits, see alignment E=1.1e-48 PF12974: Phosphonate-bd" amino acids 119 to 241 (123 residues), 31.1 bits, see alignment E=1.6e-11

Best Hits

Swiss-Prot: 44% identical to Y1080_HAEIN: Probable amino-acid ABC transporter-binding protein HI_1080 (HI_1080) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 92% identity to azl:AZL_c01360)

Predicted SEED Role

"L-Cystine ABC transporter, periplasmic cystine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (257 amino acids)

>MPMX19_05074 L-cystine-binding protein TcyA (Azospirillum sp. SherDot2)
MKWLKSLLVAGLMQVAAVSAAHAQADLDRIKADGVLKIGTEGTYAPFTYHDASGALVGFD
VEIGREIAKRIGVKAEFLEGKWDGLIAGLDARRYDAVINQVGITEARKAKYDFSDPYITS
RAVLIVKGDNSAIKGFADLKGKKSAQSLTSNFGKLAEASGAQLVGTDGFDQSIQLVLNGR
ADATVNDSLSFLDFKKHKPDANVKIAATQDNADQSGIIVRKGEAKLVSAINEALTAMKAD
GTYATISQKYFGADVSK