Protein Info for MPMX19_05035 in Azospirillum sp. SherDot2

Annotation: ATP synthase subunit a

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 77 to 98 (22 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 166 to 190 (25 residues), see Phobius details amino acids 199 to 221 (23 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 24 to 215 (192 residues), 119 bits, see alignment E=1.4e-38 PF00119: ATP-synt_A" amino acids 24 to 214 (191 residues), 152.7 bits, see alignment E=7e-49

Best Hits

Swiss-Prot: 59% identical to ATP62_BRASB: ATP synthase subunit a 2 (atpB2) from Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 95% identity to azl:AZL_c00780)

MetaCyc: 40% identical to ATP synthase Fo, a subunit (Synechococcus elongatus PCC 7942 = FACHB-805)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>MPMX19_05035 ATP synthase subunit a (Azospirillum sp. SherDot2)
MTESPLTTPVVFLLGPVPVTPPVVVTWGLMAAMALGSALATRRLRVERPGPVQTVLELVV
ETLRRQIAETMQTDATPFLPLLGTLFLYLAVANLSGLVPGLKAPTAFLETAAALALIVLL
ASQALGIRRRGLWNYLKGFAHPTPILLPLNLLSELTRAFSLSIRLFGNVMSGEFVIAIVL
SLAGLFVPVPLMALELLLGLVQAYIFTILAAVFIGGAVGTIEKG