Protein Info for MPMX19_05032 in Azospirillum sp. SherDot2

Annotation: ATP synthase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 TIGR00962: ATP synthase F1, alpha subunit" amino acids 29 to 487 (459 residues), 582.7 bits, see alignment E=3.2e-179 PF00006: ATP-synt_ab" amino acids 159 to 374 (216 residues), 250.5 bits, see alignment E=1.4e-78 PF00306: ATP-synt_ab_C" amino acids 381 to 489 (109 residues), 83.3 bits, see alignment E=2e-27

Best Hits

Swiss-Prot: 59% identical to ATPA3_PARXL: ATP synthase subunit alpha 3 (atpA3) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K02111, F-type H+-transporting ATPase subunit alpha [EC: 3.6.3.14] (inferred from 68% identity to rce:RC1_0368)

MetaCyc: 51% identical to ATP synthase F1, alpha subunit (Synechococcus elongatus PCC 7942 = FACHB-805)

Predicted SEED Role

"ATP synthase alpha chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (509 amino acids)

>MPMX19_05032 ATP synthase subunit alpha (Azospirillum sp. SherDot2)
MTPQDTVPTPLLEEALDAWMPGTLRRLDGLETAARLESVGRVESVGDGIAHVSGLPDVRV
DELLLFPGGVAGLAMDLDGQIGCVLLGDAAVVMAGGTVHGTGTVLRVPVGDGLMGRVVDP
LGNPLDDGPPVEAERWEPVERPAPTIAERAAVSEPLLTGTAVIDAMFPLGRGQRELLIGD
RATGKTAIAVDAILNQTDGDVFCVYVAVGQKASGVRAAIEAVRQGGAAARTLFVIAAADS
APGLQWLAPYAGFTMAEHFRDSGRHALVIVDDLSKHAAVHRQLSLLLRRPPGREAYPGDV
FYLHSRLLERAAKLSPARGGGSLTALPIAETQGGNLSAYIPTNLISITDGQVCLDAKLFY
EGQKPAVDIGRSVSRVGGKAQPPVLRTLAEPLRLDYAQFLELEVFTRFGGLVDERTRKAV
AHGQRMRALLAQRHLSPRPLAVQAAQLLALADGTLDGLPLEAIQRFQTALAGLVAARPPK
IGEALDDATRTALRDLIAQATAGLGGGTP