Protein Info for MPMX19_04992 in Azospirillum sp. SherDot2

Annotation: Chaperone protein ClpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 894 TIGR03346: ATP-dependent chaperone protein ClpB" amino acids 6 to 854 (849 residues), 1241 bits, see alignment E=0 PF02861: Clp_N" amino acids 17 to 68 (52 residues), 45.8 bits, see alignment 3.8e-15 amino acids 98 to 147 (50 residues), 26.8 bits, see alignment 3.3e-09 PF00004: AAA" amino acids 206 to 317 (112 residues), 47.8 bits, see alignment E=1.4e-15 amino acids 601 to 719 (119 residues), 29.9 bits, see alignment E=4.7e-10 PF17871: AAA_lid_9" amino acids 345 to 445 (101 residues), 116 bits, see alignment E=5.1e-37 PF07724: AAA_2" amino acids 595 to 758 (164 residues), 216.9 bits, see alignment E=1.2e-67 PF07728: AAA_5" amino acids 600 to 720 (121 residues), 44 bits, see alignment E=1.6e-14 PF10431: ClpB_D2-small" amino acids 765 to 842 (78 residues), 80.8 bits, see alignment E=4.1e-26

Best Hits

Swiss-Prot: 61% identical to CLPB_RHIME: Chaperone protein ClpB (clpB) from Rhizobium meliloti (strain 1021)

KEGG orthology group: None (inferred from 96% identity to azl:AZL_c04990)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (894 amino acids)

>MPMX19_04992 Chaperone protein ClpB (Azospirillum sp. SherDot2)
MDFGQFTDRARSVIQAAQIAALAERHQQLLPEHLLKALIDEGSGVAARLVRDTGGDPDLL
KSATEEQLSRAPVQAGSSEGPQPLYMSPALAAVLQAAVASARSGGDRFVTAERLLESLAR
QSGPLRALFRRAGVDADALAAAADAQRKDHPADAETETTAGEALARYTRDLTEEARQGRL
DPVIGRDDEIRRTIQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRLASGDVPEGLKDRRV
LSLDLTALLAGAKFRGEFEERLKSVLSEVQEANGRIILFIDELHTLIGAGRTDGAMDAAN
MLKPALARGELRCVGATTPDEYRKYIEKDAALARRFQPVTVDEPSADDAVSILRGIKGKY
EVHHGVRIADAAVVAAVSLSARYIGDRRLPDKAIDLVDEAASRLRMAIDSKPEALDAVDR
RVAQLKIEREALKAEPDAASQERLHVLDGELIEAEARQTSMEEEWRASQSRRTEGRRLKE
ELDQARTKLERAQRDGDWAKAGELAYGVVPDLEKRLAEAESRASAERDEVTAKDIGAVVT
RWTGIPVERMLEGERQRLKGMEDKLAERVVGQKEAVRAVSKAVRRARAGLKDPSRPTGSF
LFLGPTGVGKTELAKALASFLFDDETAITRLDMSEYMEKHAVSRMIGSPPGYVGYDDGGS
LAERIRRRPYQVVLLDEVEKAHPDVLNVLLQALDDGRLTDGQGRTADFRHAILIMTSNLG
AEALSALGDDEDMAGVTVEVMDAVRKAFRPEFLNRLDDVLIFRRLGRDQMSRIVDIQLSR
VNERLAERGVTLAADAAAKRRLGDLGWDPAFGARPLKRAIQGLVEDPIAERLLDEEVEGK
TTMTLSVVDGQLALDGVVVEEDRAHGFKAPERPPLGFSLPPVASSAASREASVH