Protein Info for MPMX19_04971 in Azospirillum sp. SherDot2

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 877 TIGR00229: PAS domain S-box protein" amino acids 63 to 180 (118 residues), 31.9 bits, see alignment E=6.5e-12 amino acids 198 to 248 (51 residues), 26.6 bits, see alignment 2.8e-10 PF00989: PAS" amino acids 67 to 173 (107 residues), 22.8 bits, see alignment E=2.6e-08 amino acids 199 to 308 (110 residues), 41.2 bits, see alignment E=5.4e-14 PF13426: PAS_9" amino acids 79 to 178 (100 residues), 15.7 bits, see alignment E=5.1e-06 amino acids 209 to 334 (126 residues), 31.6 bits, see alignment E=5.8e-11 PF13188: PAS_8" amino acids 200 to 239 (40 residues), 21.1 bits, see alignment 8e-08 PF08448: PAS_4" amino acids 205 to 336 (132 residues), 33.9 bits, see alignment E=1.2e-11 PF00512: HisKA" amino acids 511 to 576 (66 residues), 44.2 bits, see alignment 5.7e-15 PF02518: HATPase_c" amino acids 621 to 730 (110 residues), 96 bits, see alignment E=6.8e-31 PF00072: Response_reg" amino acids 756 to 871 (116 residues), 51.1 bits, see alignment E=4.8e-17

Best Hits

KEGG orthology group: None (inferred from 83% identity to azl:AZL_c05230)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (877 amino acids)

>MPMX19_04971 Sensor histidine kinase RcsC (Azospirillum sp. SherDot2)
MTEDSSGRLRRRAETILNGGNFEATDVTAASMKELLHELYVHQAELEIQNEELRGAQQAL
EASRLQYLQLFQSVPLACLAVNAAGIVGEANAAAERQFGLPMLRLKGRPLTLLLDSVDHG
RLFTALGRLRDHGDWVRQEFRYLGPHGTIIDGLTDARRVTLDDSDRGDVLLTITDLTERN
AWLREVQQARDDAERARADYHHILQSVGDGILGVDADGRIRFVNAAATAMTGHLDLDLIG
RPPSDLFAGLAEAGLPVGETDPAAFQAGGAARALALSLTDGRPRSVACEKLRREDGGTLL
VEITISPMLASGMRLAPMQDRIQGAVVAFRDVTARRTAEAALNLSERRHRVLVQSLHDAL
AMTAVDGRCLLANAMAERLLDGPAGALLDPMASAFDADGKAESRADGQLVPATAPSTMVP
TTAGRRFIDANGNRLHGLPPAAEAVRSGKPVVERIIGVVEGEEATAPTRWLRVSSRPVAD
PAGRVEAVVSSVADITAVKALERELNVALDARERFLAAASHDLRQPVQALLLLSDLLMKE
TLAPGAQRMAEQIQSSLGGLGGMLDGMLDISKLEAGLVAPNPESVDIAALLARLHGEFAP
AAEKAGQALRLVAPPLTTRTDPRLLERVLRALLANALHFAPGGRVLIGARQRGDHVQIEV
WDTGIGIADQHIDRIFQDFYQVGNAARDRREGLGLGLSIAKRLVTMLDGTIDVTSSLGRG
SRFTVSLPLTETRPDMTDRSGSAGRSGADDEAGRLVMLVEDDAVIRMALVLMLEDWNYRV
AEAGSGAEAEQLLGELIESGEEPDLILADYRLPEGTTGLMVMDMVRRRLSRDIPGVLLTG
DTSADRLREAAGAQCALLHKPIQPGRLHDTLAAALGG