Protein Info for MPMX19_04868 in Azospirillum sp. SherDot2

Annotation: Protein YdeP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01701: oxidoreductase alpha (molybdopterin) subunit
  • amino acids 19 to 761 (743 residues), 908.1 bits, E=2.1e-277
• PF00384: Molybdopterin
  • amino acids 115 to 490 (376 residues), 63.7 bits, E=1.6e-21
• PF01568: Molydop_binding
  • amino acids 650 to 756 (107 residues), 32.7 bits, E=6.4e-12

Best Hits

KEGG orthology group: K00123, formate dehydrogenase, alpha subunit [EC: 1.2.1.2] (inferred from 72% identity to mno:Mnod_6881)

Predicted SEED Role

"Putative formate dehydrogenase oxidoreductase protein" in subsystem Formate hydrogenase

MetaCyc Pathways

• superpathway of C1 compounds oxidation to CO₂ (9/12 steps found)
• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (17/24 steps found)
• oxalate degradation VI (2/4 steps found)
• oxalate degradation III (2/5 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (762 amino acids)

>MPMX19_04868 Protein YdeP (Azospirillum sp. SherDot2)
MSIDGLSDDKDTPHYDGPAGGWGSVGSMARIMGEERPTPAVLDTLRRQNKPGGFMCVSCA
WAKPAKPRAFEFCENGAKATIWELTSRRCTPDFFAEHTVTELKGWKDYDLEQQGRLTHPM
RYDRASDRYLPCGWDEAFAAIGSELRAIDPEQAVFYASGRASLETSYLYALFARLYGHNN
LPDSSNMCHETTSVGLKTVIGSPVGTCVLDDFESCNAIFFFGQNTGSNSPRLLHPLQEAV
KRGAKIVTFNPVREKGLESFRNPQSPLEMLTGKDTRISTLYFQVKAGGDIAAITGMIKHV
LAAAEERKADGKHVLDHDFIAQHTAGFDEMKARIDAIGWEEIEEESGLTRADLKEAADIY
IEAERSIAMYGMGLTQQVRGSETLGALVNLWLLKGNIGRDGAGISPVRGHSNVQGQRTVG
ISEKPELVPLDRLAEQFGFEPPRKEGLNTVKACGKILSGEVKAFIGLGGNFVRAIPERER
MEAAWTRLRLTVQVATKLNRSHLINGEVAYLLPCLGRSEEDVQESGAQAVTMEDSLSCIH
GSLGTNTPASPHLKSEAAIVAGMAKATLPPNPKVTWDAWVADYRRIRALIEATYPDQFHH
FNERVFTPGGFYRGNPARERIWKTDSGKAHFTPPGRLRAIGFEDAPGRWRLMTMRSNDQF
NTTIYGYSDRLRGIEGTRDVLLMNPLDIAAAGLQEGQVVALASDAGDDVDRRVGGLTVTP
FHLPRGCLGAYYPEMNPLIPLWYHDEASKTPAAKGVPVRIVA