Protein Info for MPMX19_04854 in Azospirillum sp. SherDot2

Annotation: Hexuronate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 47 to 68 (22 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 103 to 119 (17 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 225 to 247 (23 residues), see Phobius details amino acids 263 to 287 (25 residues), see Phobius details amino acids 299 to 317 (19 residues), see Phobius details amino acids 323 to 346 (24 residues), see Phobius details amino acids 358 to 380 (23 residues), see Phobius details amino acids 388 to 408 (21 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 330 (316 residues), 164.4 bits, see alignment E=1.7e-52

Best Hits

Swiss-Prot: 50% identical to EXUT_ECOLI: Hexuronate transporter (exuT) from Escherichia coli (strain K12)

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 95% identity to azl:AZL_c04530)

MetaCyc: 50% identical to hexuronate transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-123; TRANS-RXN-35

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>MPMX19_04854 Hexuronate transporter (Azospirillum sp. SherDot2)
MNKIRGLRWQILALMMLGTVVNYIDRNTLGILAPTLKEQLHFTTEQYSFIVSAFQLCYSL
MQPVAGYITDLIGLKLGYAMFAGVWGIAAAMHALAGSWQSMAFFRGLLGVSEAAAMPSGV
KTSTLWFPAKERSIATGWFNTGSSIGAMIAPPFVIWLSLTYGWQEAFLVTGLLGVGMSAL
WYMLYRNPENHPRLTKEEHAYILDGQEQVELPKPSMKRVLGKGKFWSIAAARFLTEPAWQ
TFSFWIPLYMVSTRGMDIKQFALFAWLPFLAGDIGCILSGYLSPFFVKRFKMSLVNSRIA
GVGVGAVCMIGPALISFTVSPIAAIFLFSLGAFAHQMLSSLLYALVTDTFEKQDVATATG
FGGMAGYMGGMIFSLMIGQLATTIGYEPLFACLTVFDLAAFAIIALVLGQRGPKSAAAVP
NATAGAD