Protein Info for MPMX19_04853 in Azospirillum sp. SherDot2

Annotation: Pyruvate-flavodoxin oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1195 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 23 to 1191 (1169 residues), 1690.5 bits, see alignment E=0 PF01855: POR_N" amino acids 33 to 263 (231 residues), 288.6 bits, see alignment E=2.2e-89 PF17147: PFOR_II" amino acids 285 to 371 (87 residues), 46.7 bits, see alignment 1.9e-15 PF01558: POR" amino acids 447 to 630 (184 residues), 108.2 bits, see alignment E=3.1e-34 PF10371: EKR" amino acids 648 to 699 (52 residues), 89.3 bits, see alignment (E = 6.2e-29) PF12837: Fer4_6" amino acids 703 to 725 (23 residues), 26.3 bits, see alignment (E = 2.9e-09) PF00037: Fer4" amino acids 705 to 726 (22 residues), 26.3 bits, see alignment (E = 2.7e-09) PF13237: Fer4_10" amino acids 706 to 777 (72 residues), 25.1 bits, see alignment 7.3e-09 PF12838: Fer4_7" amino acids 710 to 778 (69 residues), 37.9 bits, see alignment 1.1e-12 PF02775: TPP_enzyme_C" amino acids 981 to 1091 (111 residues), 32.6 bits, see alignment E=3.6e-11

Best Hits

KEGG orthology group: K03737, putative pyruvate-flavodoxin oxidoreductase [EC: 1.2.7.-] (inferred from 62% identity to ank:AnaeK_0230)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.-

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1195 amino acids)

>MPMX19_04853 Pyruvate-flavodoxin oxidoreductase (Azospirillum sp. SherDot2)
MIKSPTSTAPIRSASSVRIMARIMDGNEAAASVAYRASDVIAIYPITPSSPMGEFADEWS
AAHRPNLWGSVPQVVEMQSEGGAAGAVHGALQAGALATTFTASQGLLLMIPNMYKIAGEL
TPFCMHVAARTLATHALSIFGDHSDVMACRQTGFAMLASANVQEAQDLALVAHAATLRAR
VPFLHFFDGFRTSHEFNCIEPLADDDLRALIDDRCVDAHRRRGLTPDHPVVRGTAQNPDV
FFQAREAANPWYDACPAIVQEMMDRLAARTGRAYRLFDYHGHPQAERVVVVMGSGAETCN
GTVDRLLEQGERVGCLTVRLFRPFAIADFVSTLPATVRRIAVLDRTKEPGAVADPLYLDV
VAALAEARAADSSAIDPIVVAGRYGLSSKEFTPAMAKAVFDELGRDRPKRRFTVGITDDV
THHSIRWDADWAVEEPGVSRAVFFGLGADGTVGANKNSLKIIQSRSGGHAQAYFVYDSRK
SGSTTVSHLRFSKEPIRAPYLIGQAQFVACHHLPLMERVEVAEMAAPGATLLLNAPGTPQ
QVWDALPAEVQRLCIERRLSLHAIDAGAVAREVGLGRRVNTIMQTCFFALSNVMPVEDAI
AEIKAAIAKTYSRRGDEVVARNIAAVDRALAHLHPVPVPDHVTADHVRPAPVPETAPDFV
KRVTAMMIAGHGDRLPVSAFPVDGTWPTGTSKYERRNIAAEAPGWNADLCIECNKCVLVC
PHAAIRATVVPESALAGAPAGFETIPYKGREFPGGRYRLQASPADCTGCTLCVAACPVED
KAGSGRKALEMRPIQALAGQQEAFDFFRNLPAIPRESVPVTVKHSQLLEPLFEFSGACAG
CGETPYIKMLTQLFGDRMVMANATGCSSIYGGNLPTTPYTTDASGHGPAWANSLFEDNAE
FGLGLRVAIDGMAEQARDALALLSAQLEPGLVTELLEAGQNDAAGIAAQRTHVATLRTQL
ALLKDPLARRLEQLADYLVRKCVWIVGGDGWAYDIGYGGLDHALASGRDINILVMDTEVY
SNTGGQQSKATPIGASAKFATAGRSAAKKDLGLMAMAYDHVYVARTAFGARDSHTLNALT
EAEAYRGPSLVLAYSHCVAHGFELSHGLEHQKLAVDSGHWSLYRRDPQRLAKGKTALQLD
SGAPSAGLAAFMAGESRFSAVERANPERFHALLDEAEAEIRRKRHLFEHMAGFKE