Protein Info for MPMX19_04581 in Azospirillum sp. SherDot2

Annotation: Formamidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 PF03069: FmdA_AmdA" amino acids 8 to 384 (377 residues), 619.4 bits, see alignment E=1e-190

Best Hits

Swiss-Prot: 73% identical to FMDA_METME: Formamidase (fmdA) from Methylophilus methylotrophus

KEGG orthology group: K01455, formamidase [EC: 3.5.1.49] (inferred from 83% identity to azc:AZC_4101)

MetaCyc: 57% identical to formamidase subunit (Paracoccidioides brasiliensis)
Formamidase. [EC: 3.5.1.49]

Predicted SEED Role

"Formamidase (EC 3.5.1.49)" (EC 3.5.1.49)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.49

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (410 amino acids)

>MPMX19_04581 Formamidase (Azospirillum sp. SherDot2)
MADTLIKADLSQSPYENDMIHNRWHPDIPMAVTVKPGDDFILECYDWTGGQIKNDDDAAD
VRDVDLSQVHFLSGPVGVEGAEPGDLLVVDLLDIGAFPQQQWGFNGFFSKQNGGGFLTEH
FPLAQKSIWDFEGMFTKSRHIPGVRFAGLIHPGLIGCLPSHDLLAKWNKREQALIDTNPT
RVPGLANPPYAPTAHMGRLKGDARDKAAAEGARTVPPREHGGNCDIKDLSRGSRIYFPVY
VKGAGLSMGDLHFSQGDGEITFCGAIEMAGWAHLKVNLIKDGMAKYGIRNPIFKPSPIVP
TYNDYLIFEGISVDEAGEQHYLDVHVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQG
HISGVVDVPNACATLFLPTQIFDFDITPNADGPTKFISGDVDMPVAPDRV