Protein Info for MPMX19_04538 in Azospirillum sp. SherDot2

Annotation: Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 35 to 370 (336 residues), 198.6 bits, see alignment E=3.5e-62 PF13433: Peripla_BP_5" amino acids 39 to 113 (75 residues), 39.1 bits, see alignment E=7.8e-14 amino acids 169 to 361 (193 residues), 36.1 bits, see alignment E=6.4e-13 PF01094: ANF_receptor" amino acids 59 to 368 (310 residues), 94.1 bits, see alignment E=1.4e-30

Best Hits

KEGG orthology group: None (inferred from 58% identity to bch:Bcen2424_6643)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (377 amino acids)

>MPMX19_04538 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein (Azospirillum sp. SherDot2)
MARMNGMTRRSAGGALLGAMALAMLSSGAARAQDTVTLGAVLPLSGASATIGEDQRRGIE
LAVEKINADGGVLGRKLAVAVEDSGGRAQSAVDAARKLVSVSKTPVVIGEYSSGNTIPVG
QYLQREGIVHINPGSSSPAIKTIGDRSFSTIGLDDVAGKFTAQAVYGMGHRKAVFLAPNN
AYGQGVYSETKAAFEALGGQIVANLLFTEGQSNYRRELQRIAAAKPDVIIYSGYGQEAAT
INREAFELGLSKTPWFGIYLSMCTADSRPETVEGQMGMEVNYVGPDGAWYRDAYKKKFGK
EFATTFSGYTYDAVMMAAAAINRAGSTEPAKIREALAALGDYAGATGPIAFDAQGQRKAQ
PYIVVSYKGGELKTAAK