Protein Info for MPMX19_04533 in Azospirillum sp. SherDot2

Annotation: HTH-type transcriptional regulator NimR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF07883: Cupin_2" amino acids 37 to 96 (60 residues), 31.1 bits, see alignment E=3.2e-11 PF02311: AraC_binding" amino acids 38 to 113 (76 residues), 36.1 bits, see alignment E=1e-12 PF12833: HTH_18" amino acids 185 to 262 (78 residues), 72.7 bits, see alignment E=5e-24

Best Hits

Swiss-Prot: 50% identical to NIMR_ECOLI: HTH-type transcriptional regulator NimR (nimR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 82% identity to rru:Rru_A1951)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>MPMX19_04533 HTH-type transcriptional regulator NimR (Azospirillum sp. SherDot2)
MPNAMSGSRSAVSVFDPDLADRPAVARLLDFADYEAEVPVHVHRRGQLILALHGAVTCTA
DDEIWIVPPDCGVWIPGGMPHSVRTTANARLSYLFVEPGAANLPEVCCTLSISPLVRELV
NRLTGEVLDYPPDSHAARLARVTLDELAGMPREHFNLPISNDPKIRAIADALTLEPSDRS
TLGDWARRVAMSERSLARLMLRETGLTFGRWRQQLHLVVALRELAGGAAVQTVADTLGYE
SVNAFITMFKKALGSTPAQYFTQRRAKLSALSR