Protein Info for MPMX19_04437 in Azospirillum sp. SherDot2
Annotation: Oxalyl-CoA decarboxylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to OXC_OXAFO: Oxalyl-CoA decarboxylase (oxc) from Oxalobacter formigenes
KEGG orthology group: K01577, oxalyl-CoA decarboxylase [EC: 4.1.1.8] (inferred from 98% identity to azl:AZL_a03520)MetaCyc: 60% identical to oxalyl-CoA decarboxylase monomer (Oxalobacter formigenes)
Oxalyl-CoA decarboxylase. [EC: 4.1.1.8]
Predicted SEED Role
"Oxalyl-CoA decarboxylase (EC 4.1.1.8)" in subsystem Alkaloid biosynthesis from L-lysine (EC 4.1.1.8)
MetaCyc Pathways
- oxalate degradation II (2/3 steps found)
- oxalate degradation VI (2/4 steps found)
- oxalate degradation III (2/5 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.1.1.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (587 amino acids)
>MPMX19_04437 Oxalyl-CoA decarboxylase (Azospirillum sp. SherDot2) MSTAAATITKNQATEASVVEDAPALTDGFQLVIDALKLNDINNLYVVPGIPISDLLRMAQ AEGMRVVSFRHEQNAGNAAAIAGFMTKKPGVCMTVSAPGFLNGLTALANATTNCFPMILI SGSSEREVVDLQQGDYEEMDQLAIAKPLCKAAFRILHAQDIGIGVARAIRAAVSGRPGGV YLDLPAKLFSQVMDAAEGAKSLVKVVDPTPAQYPSAEAVNRALDLLKGAKRPLVIFGKGA AYAQADETIRSFVEKSGIPFLQMSMAKGLLPDTHPQSAGAARSLVLQEADVVMLVGARLN WLLSHGKGKTWGKPGSKKFIQVDIEPREMDSNVEIHAPLVGDIASVMEVMLKGIDGGLTP PTDWMATVAAKREQNVAKMAPKLMSNASPMNFHGALGALRRIIKERPDALLVNEGANTLD LARGIIDMYEPRKRLDVGTWGVMGVGMGYAVAAAVESGKPVLAVEGDSAFGFSGMEVETI CRYNLPVCIVIFNNNGIYRGTDVNPTGGNDPSPMVFVPGSRYDKMMEAFGGVGVHVTNPD ELYRAVNEAMDSGRPTLINAVIDPAAGTESGNIGSLNPTSSVRKMPS