Protein Info for MPMX19_04436 in Azospirillum sp. SherDot2

Annotation: Formyl-CoA:oxalate CoA-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 TIGR03253: formyl-CoA transferase" amino acids 3 to 415 (413 residues), 727.9 bits, see alignment E=1.6e-223 PF02515: CoA_transf_3" amino acids 5 to 391 (387 residues), 331.9 bits, see alignment E=2.7e-103

Best Hits

Swiss-Prot: 80% identical to FCTA_RHOP2: Formyl-CoA:oxalate CoA-transferase (frc) from Rhodopseudomonas palustris (strain HaA2)

KEGG orthology group: K07749, formyl-CoA transferase [EC: 2.8.3.16] (inferred from 98% identity to azl:AZL_a03530)

MetaCyc: 63% identical to formyl-CoA transferase (Escherichia coli K-12 substr. MG1655)
Formyl-CoA transferase. [EC: 2.8.3.16]

Predicted SEED Role

"Formyl-coenzyme A transferase (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>MPMX19_04436 Formyl-CoA:oxalate CoA-transferase (Azospirillum sp. SherDot2)
MGKALQGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGEGDITRSQLRDLPDADSLYF
TMLNHNKRSITLDTKTPKGKEVLEALIKTCDVMVENFAPGVLDRMGFTWERIQELNPAMI
VASVKGFGPGPFENCKVYENVAQCAGGAASTTGFDDGPPMVTGAQIGDSGTGLHLALGIV
TALYQRRETGRGQKVLAAMQDAVLNLCRVKLRDQQRLANGPMKEYPQYPNGEFGDTVPRA
GNASGGGQPGWILKCKGWETDPNAYIYFIAQAPVWKSICKVIGKEEWITDPDYATPVARL
PRLMQIFATVEEWTKTLTKFEVMDLLNKYDIPCGPILSMKEIAEDKSLYETGTLVEVEHP
TRGSYLTVGNPIKLSDSPTEVTRSPLLGEHTDEILRDVLGFGEREIVEIRDSGAIGVVER
LAAE