Protein Info for MPMX19_04329 in Azospirillum sp. SherDot2

Annotation: Deoxyguanosinetriphosphate triphosphohydrolase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 TIGR01353: putative dGTPase" amino acids 32 to 393 (362 residues), 331.3 bits, see alignment E=6e-103 PF01966: HD" amino acids 70 to 209 (140 residues), 59.3 bits, see alignment E=4.7e-20 PF13286: HD_assoc" amino acids 298 to 391 (94 residues), 99.9 bits, see alignment E=9.9e-33

Best Hits

Swiss-Prot: 64% identical to DGTL1_PARL1: Deoxyguanosinetriphosphate triphosphohydrolase-like protein (Plav_3021) from Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 96% identity to azl:AZL_a04460)

Predicted SEED Role

"Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)" in subsystem Purine conversions (EC 3.1.5.1)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>MPMX19_04329 Deoxyguanosinetriphosphate triphosphohydrolase-like protein (Azospirillum sp. SherDot2)
MTADCSHDRLAPYGCNPADTRGRLVAEPESPTRSCFQRDRDRIVHSGAFRRLKHKTQVFV
YHEGDYYRTRLTHSLEVAQIARSISRTLGLNEDLAEAVALAHDLGHTPFGHAGEEALNAC
MEPFGGFAHNDQTLRILTRLERRYAEFDGLNLTWEALEGVVKHNGPLLPLHPGHRLPTTI
AAFQGDWDLELDTNPGAEAQVAALADDIAYNNHDIDDGLRAGLFTVDEVAELPLVGPLVR
EVCDRYPGLERSRLIHETIRRMINAMVVDLVTETRRRLAEHRPGSAAELRALPLAMAGFS
DGMLEAQRPLRAFLRQRMYRHYRVNREMSKCKRVVRALFQLFMDEPNTLPTEWQRDIAQN
GGDADLAVRARHVADYIAGMTDRYALAEHDRLFDLHVKT