Protein Info for MPMX19_04052 in Azospirillum sp. SherDot2

Annotation: putative sugar-binding periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF13416: SBP_bac_8" amino acids 59 to 361 (303 residues), 94.3 bits, see alignment E=1.1e-30 PF01547: SBP_bac_1" amino acids 62 to 333 (272 residues), 113.7 bits, see alignment E=1.8e-36

Best Hits

Swiss-Prot: 50% identical to SP39_BRUAB: Probable sugar-binding periplasmic protein (BruAb2_0537) from Brucella abortus biovar 1 (strain 9-941)

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 97% identity to azl:AZL_a07960)

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (430 amino acids)

>MPMX19_04052 putative sugar-binding periplasmic protein (Azospirillum sp. SherDot2)
MSKMPSLSNSILGMTATSMVALATVMAGALMAAPAQAEPAVEVLHYWTSGGESKAAGALR
QDFEAAGGKWIDAPVAGGGGDAASTVLRSRVLAGDPPNAVQLKGPNIKDWAAQGKLATLD
EVAKAENWDAILPPQIRDVVTYKGHYYAVPVNIHRVNWMWVNPKVMEKAGVAIPKTWDEF
NAAADKLKAAGIIPLAHGGQPWQEGALFEDVTLGLGGPDFYRKALVELDAKTLTSDTMVK
VFDQMRKLRGYVDDGFPGREWNLAAGLLMNGQAAMQIMGDWEKGELTAAGKVPGKDFVCA
HVPGQFGYIVNSDSFVMFSSANADRAAGQKLLAKLILGKKFQETFNVLKGSIPARQDMAR
DSFDECAVKSMDDLKTAIDTNSAVPSMAHEMAVPGAVRGAFLDVVTAHFNSTMTSQEAVK
RLAEAVDLAK