Protein Info for MPMX19_04051 in Azospirillum sp. SherDot2

Annotation: Alcohol dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 PF08240: ADH_N" amino acids 27 to 146 (120 residues), 73.7 bits, see alignment E=2e-24 PF00107: ADH_zinc_N" amino acids 186 to 315 (130 residues), 102.9 bits, see alignment E=1.9e-33 PF13602: ADH_zinc_N_2" amino acids 219 to 343 (125 residues), 56.5 bits, see alignment E=8.8e-19

Best Hits

Swiss-Prot: 74% identical to ADH_CUPNH: Alcohol dehydrogenase (adh) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: None (inferred from 96% identity to azl:AZL_a07970)

Predicted SEED Role

"Threonine dehydrogenase and related Zn-dependent dehydrogenases" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (357 amino acids)

>MPMX19_04051 Alcohol dehydrogenase (Azospirillum sp. SherDot2)
MVMMKAAVFVEPGRIVLDDKPIPDVGPLDALIRITTTTICGTDIHILKGEYPVARGLTIG
HEPVGIVEKLGSAVTGYREGQRVIAGAITPSGHSNACLCGCHSQDGAGTRHGWKPLGGWR
FGNSIDGSQAEYLLVPDAMVNLAPVPDGLTDEEVLMCPDIMSTGFAGAERGNIRIGDTVA
VFAQGPIGLCATAGARLKGATTIIAVDTVPVRLEMARRMGADHAVDFRQTDPVEEIMRLT
DGRGVDVAIEALGTQATFEAALRVLRPGGTLSSLGVYSGDLRLPLGPFAAGLGDHTIVTS
LCPGGKERMRRLMGVVASGRVDLKPLVTHRFPLERIEDAYDLFGHQRDGVLKVAITP