Protein Info for MPMX19_03974 in Azospirillum sp. SherDot2

Annotation: putative lipid II flippase MurJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details amino acids 20 to 20 (1 residues), see Phobius details transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 124 to 147 (24 residues), see Phobius details amino acids 158 to 180 (23 residues), see Phobius details amino acids 186 to 204 (19 residues), see Phobius details amino acids 228 to 254 (27 residues), see Phobius details amino acids 271 to 288 (18 residues), see Phobius details amino acids 311 to 334 (24 residues), see Phobius details amino acids 349 to 369 (21 residues), see Phobius details amino acids 381 to 400 (20 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details amino acids 445 to 461 (17 residues), see Phobius details amino acids 480 to 501 (22 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 3 to 500 (498 residues), 461.1 bits, see alignment E=2.3e-142 PF03023: MurJ" amino acids 27 to 467 (441 residues), 400.2 bits, see alignment E=2.1e-123 PF13440: Polysacc_synt_3" amino acids 83 to 335 (253 residues), 23.7 bits, see alignment E=5.3e-09 PF01554: MatE" amino acids 233 to 395 (163 residues), 26.2 bits, see alignment E=1.2e-09 PF14667: Polysacc_synt_C" amino acids 352 to 500 (149 residues), 41.8 bits, see alignment E=2.4e-14

Best Hits

KEGG orthology group: K03980, virulence factor (inferred from 95% identity to azl:AZL_a02720)

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>MPMX19_03974 putative lipid II flippase MurJ (Azospirillum sp. SherDot2)
MFRHILSVGGLTLASRVLGFLRDVLTAALLGAGPVADAFFVAFRLPNHFRALFAEGAFNS
AFVPLFSGKLVQDGVASARRFADEVMTLLVIVQMVLLLAVLAFMPQFMTVFAPGFADEPE
KFRLAVLFTSITFPYLLLISLVSLYGGVLNSMSRFGSAAAAPILMNLCLIAALVIGTPLM
PTAGHALSWGVLASGVAQFLYLAWDARRADMTLRPVMPRLSPDVKRFLKVLGPAALGSGL
TQISLFADTLIASALPTGAVSYLYYADRLNQLPLGVIGIAVGTVLLPEMSKRIKSGDEAG
AVDSQNRAIELSLVLTLPAAIAFLVAGTPILSVLFQRGAFGPSDAAASALTLQAYALGLP
AFVVIRSLVNGFYARHDTATPVRVALAAVGINVALKLALMGPLAQVGLAVATSVGAWVNA
GLLALLLHRRGLFRADARLTRNLPRMAIAAVAMAGALWLATERLAPWLGAVGVAERLGGL
LVLAAVGLTVYAVAAVLLGLVRRSDLSRLRRRRAKA