Protein Info for MPMX19_03747 in Azospirillum sp. SherDot2

Annotation: Potassium-transporting ATPase KdpC subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR00681: K+-transporting ATPase, C subunit" amino acids 4 to 197 (194 residues), 228.6 bits, see alignment E=3.1e-72 PF02669: KdpC" amino acids 5 to 196 (192 residues), 258.5 bits, see alignment E=1.6e-81

Best Hits

Swiss-Prot: 74% identical to KDPC_METRJ: Potassium-transporting ATPase KdpC subunit (kdpC) from Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)

KEGG orthology group: K01548, K+-transporting ATPase ATPase C chain [EC: 3.6.3.12] (inferred from 74% identity to mrd:Mrad2831_0206)

MetaCyc: 46% identical to K+ transporting P-type ATPase subunit KdpC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>MPMX19_03747 Potassium-transporting ATPase KdpC subunit (Azospirillum sp. SherDot2)
MLKDLRPALVMTVALTAITGLAYPLAVTGIAQVLFPHQANGSLIERNGTTVGSSLIGQDF
TAAGYFHPRPSATTGADPADPAKTVPAPYNAANSMGSNLGPTSKALVDRVQADAEKLKAE
NPGAPVPVELVTTSGSGLDPDLSPAAADFQVPRVAKARGLPEDAVRKLVADTTEPRPLGF
LGEPTVNVLALNLALDRAAGKAAGK