Protein Info for MPMX19_03649 in Azospirillum sp. SherDot2

Annotation: Trehalose transport system permease protein SugA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 65 to 94 (30 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 155 to 178 (24 residues), see Phobius details amino acids 208 to 231 (24 residues), see Phobius details amino acids 262 to 282 (21 residues), see Phobius details PF00528: BPD_transp_1" amino acids 88 to 288 (201 residues), 51.1 bits, see alignment E=7.2e-18

Best Hits

KEGG orthology group: K10228, sorbitol/mannitol transport system permease protein (inferred from 98% identity to azl:AZL_b04830)

MetaCyc: 60% identical to polyol ABC-type transporter permease component MtlF (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, permease component 1" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>MPMX19_03649 Trehalose transport system permease protein SugA (Azospirillum sp. SherDot2)
MATAHSRAAARLTMSPAVILLLGWMLIPLVMTLYFSFLRYNLLMPGTEEFIGTLNYQYFL
TDPAFFAALFNTLALVGGVLVLTIAGGIGLALLLDQPFWGRGIVRLLVIAPFFVMPTVSA
LVWKNMLMNPVNGLFAAIAKGLGLQPFDFLAEAPLSSIILIVTWQWLPFATLILLTALQS
LDRERLEASEMDGAGAVDRFIHIILPHLARAMTVVTLIQTIFLLSVFAEILVTTNGGPGT
ATTNITYLVYAQSLLQFDVGGGSAGGIVAVVLANIVAVFLMRMIGRNLDI