Protein Info for MPMX19_03632 in Azospirillum sp. SherDot2

Annotation: Sodium, potassium, lithium and rubidium/H(+) antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 32 to 51 (20 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 158 to 178 (21 residues), see Phobius details amino acids 185 to 207 (23 residues), see Phobius details amino acids 225 to 248 (24 residues), see Phobius details amino acids 267 to 288 (22 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details TIGR00831: Na+/H+ antiporter" amino acids 10 to 520 (511 residues), 288.6 bits, see alignment E=4.5e-90 PF00999: Na_H_Exchanger" amino acids 14 to 404 (391 residues), 197 bits, see alignment E=2.3e-62

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 94% identity to azl:AZL_b04910)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>MPMX19_03632 Sodium, potassium, lithium and rubidium/H(+) antiporter (Azospirillum sp. SherDot2)
MSPSGQFELVLGLMAAIIVLELAAKRLRMPPSAVLVLGGIALALIPGLPEITPDPDLTLL
LFLPPLLFASAYFTVWSDFRANLRIILQLAVGAVAFTTLAVGVAAHLVMPSLPWAACFTL
GAILSPPDAVAAKAALKGLPLPPRIVTLLEGESLVNDATGLVLFRIAIAAGMTGTFEAGH
ASLEFLWLAIGGVAAGVVFGHIAALLLGRLRDVPLSIVGGFLAAWGSYLGGEALEVSGVL
ATVGCGLVMGRRQHDLFTAQLRTHANAVWAVAVFLMESMVFIIIGLSLRGVLGRLEAAGT
GLTDLLPMIVAVTLAMILSRFAWLFPSTYLPRFLFPSLRRRDPYPSVAVPVIMGWAAIRG
VVSLAVALSVPVEFPGRDIILATTWAVILVSILGQATTLAPLIRRMRLGGFTLERRPTLS
ESEARIRMARAALDAVRERSGTADGRQRHPRLLEQYGHRATMAERFFESEGMLTEDRREH
FAAVLAANRAARTEILGLHRGGRIHDTVLHRLEAELDLEELGAEQALAEGEAAG