Protein Info for MPMX19_03528 in Azospirillum sp. SherDot2

Annotation: Sialic acid TRAP transporter large permease protein SiaM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 25 to 26 (2 residues), see Phobius details amino acids 47 to 68 (22 residues), see Phobius details amino acids 78 to 104 (27 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 240 to 256 (17 residues), see Phobius details amino acids 277 to 295 (19 residues), see Phobius details amino acids 314 to 343 (30 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 397 to 424 (28 residues), see Phobius details PF06808: DctM" amino acids 7 to 415 (409 residues), 423.3 bits, see alignment E=9.9e-131 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 418 (402 residues), 488.8 bits, see alignment E=5.7e-151 PF03606: DcuC" amino acids 67 to 412 (346 residues), 24.4 bits, see alignment E=1.1e-09

Best Hits

Swiss-Prot: 57% identical to YIAN_ECOLI: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (yiaN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to azl:AZL_c01560)

MetaCyc: 57% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>MPMX19_03528 Sialic acid TRAP transporter large permease protein SiaM (Azospirillum sp. SherDot2)
MTITIFLGSLLGAMAIGMPIAYALLLCGVALMIHLDLFDAQIVAQNLINGADSFPLMAVP
FFMLAGEIMNTGGLAKRIVNLAMAMVGHIRGGLGYVTILAATVMASLSGSAVADAAALAT
LLVPMMVAAGHDRNRSAGLVSASAIIAPIIPPSIGFVIYGVAGNVSVTKLFLAGIFPGIL
LAVGLCGAWWYVSRKENLSPPPRRSLREVLAILREGVWALMLPVIIIVGLKFGVFTPTEA
AVVAAVYSLFVAVCVYREMSVADIYPALLGAAKTTSVVMFLVAAALVSSWLITVANLPGM
VTDLLEPLMGNQTLLLLAMMALVVAIGTAMDMTPTILILTPILVPVCKQAGIDPVYFGVL
FIINNAIGLITPPVGTVLNVVCGVSKVSMEGVIKGVWPFMLVQLVVLFLLTLFPSLVMVP
AAWLSH