Protein Info for MPMX19_03492 in Azospirillum sp. SherDot2

Annotation: 3'-5' exonuclease DinG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00573: exonuclease, DNA polymerase III, epsilon subunit family
  • amino acids 27 to 198 (172 residues), 99.6 bits, E=8.9e-33
• PF00929: RNase_T
  • amino acids 29 to 187 (159 residues), 86.4 bits, E=3.3e-28
• PF00533: BRCT
  • amino acids 228 to 293 (66 residues), 25.7 bits, E=1.1e-09

Predicted SEED Role

"DNA polymerase III epsilon subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Protein Sequence (312 amino acids)

>MPMX19_03492 3'-5' exonuclease DinG (Azospirillum sp. SherDot2)
MSLSSDTVPTDPSAGAKPGRSRPSSRRFVVIDCETTGLSTAGGDRMVSFAAIELADAVPT
GRSLSLIFNPGRKSNPHALRVHGLPDHLLRHQDPFHSVAQDILGFLQGAVLVGHNVGFDI
EFLRHEFELCGIRWMASQSVCTMQHARAQVAGRASLDAVATLFGIDVGIRARFHGAFVDA
EITSRLFQKMILGSVEMLAVPHLAPTNQIDPPPLVLQPAVPITHGINGYAFAVTGELTGL
SREAVMARIQALGGHWHHSVRKDTDYLVVGHAPGATKLDTAAARRAKYGKPDTIDEAQFF
AMVAASATRRRA