Protein Info for MPMX19_03350 in Azospirillum sp. SherDot2

Annotation: GTP 3',8-cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 TIGR03906: quinohemoprotein amine dehydrogenase maturation protein" amino acids 10 to 473 (464 residues), 741 bits, see alignment E=5e-227 PF04055: Radical_SAM" amino acids 107 to 265 (159 residues), 61.5 bits, see alignment E=1.2e-20 PF13353: Fer4_12" amino acids 110 to 213 (104 residues), 37.6 bits, see alignment E=2.6e-13 TIGR04085: radical SAM additional 4Fe4S-binding SPASM domain" amino acids 353 to 441 (89 residues), 51.5 bits, see alignment E=1e-17

Best Hits

KEGG orthology group: K06871, (no description) (inferred from 65% identity to pgv:SL003B_2488)

Predicted SEED Role

"Quinohemoprotein amine dehydrogenase radical SAM maturase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>MPMX19_03350 GTP 3',8-cyclase (Azospirillum sp. SherDot2)
MATLHLVRDDLRDVTVGDRRVLFHVPTSGLFELDRVGGALIDLFAELGEVSEEDVRRRFD
GVANPAEVIDSLRELITLRIVESGPAVKRTKPPVTISEFPLSTVVLNVNTGCNLSCTYCY
KEDLTTPAKGERMEFDTAARSVDLLLQEARGRDSVNVVFFGGEPLTNLPLIRQVVAYAEE
RGREAGVRMDFSLTTNGVLLTEETVDWLDAHRFGITISMDGPKPLHDRNRRTVGGKGSYD
VVAAKARMLLSRYRSRPVGARVTLTAGVTDVVAIHDHLKTDLGFFEVGFSPVTSGAMSAF
NLTGDELATVFDNMKTLGLAYVEAAKRGVNTGFSNMHQLMTDLTEGTTKSLPCGAGLGML
AVDKEGDLHLCHRFTGSSQPTYGNVDDGIAKDSLGSFLEGMANRTGTDCETCWIRKLCAG
GCYHESYARYADPAHPTYHYCNLMRDWIDFGIRAYAEIMVANPQFIERYVAPRRGMK