Protein Info for MPMX19_03071 in Azospirillum sp. SherDot2

Annotation: HTH-type transcriptional regulatory protein GabR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF00392: GntR" amino acids 26 to 87 (62 residues), 51.7 bits, see alignment E=5.6e-18 PF00155: Aminotran_1_2" amino acids 156 to 419 (264 residues), 85 bits, see alignment E=6e-28

Best Hits

KEGG orthology group: K00375, GntR family transcriptional regulator / MocR family aminotransferase (inferred from 86% identity to rru:Rru_A1143)

Predicted SEED Role

"Predicted transcriptional regulator of pyridoxine metabolism" in subsystem Pyridoxin (Vitamin B6) Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (496 amino acids)

>MPMX19_03071 HTH-type transcriptional regulatory protein GabR (Azospirillum sp. SherDot2)
MFKHSQLESVKAWIAHPAHSAMPLHARIQRAIRQLIVDGALGRGKPLPASRPLAKSLGVS
RDTVEAAYAQLHAEGFIDRRVGSGSFVAEMTEFTPGLRLSRRDALARNQAPNLSRRGAAM
SRSGGVREMMIPRPFAHGVPETRTFPLRLWERLERQVRKEASGQTLFHGDPQGTEPLRRA
IADYVNLERGARATADRVLILTSSQQAMSLCANMLLDPGDRIFIEDPAYYGARKAFDAAG
LECVPVRVDRQGIVVDQIIAEPRKAKAVSLTPSHQFPTGATLALDRRLALIEWASRHQAW
IIEDDYDSEFHYAGKPTACLQGLDVHDRTIYIGTFTKSLFPGLRIGYVVLPPQLVKPMTV
ARTLLDGHSAPMPQLTLARFMEGGHFGAYVRTMRAIYAERLDVLVDLVQKHLSDFVEPRV
PIGGLQMPCLLIGDLSERMAIDAGRRVGVELLGLTALYATSDAKGGFLMGFAAYTPAEIE
NAVKKLANAFLAVVKP