Protein Info for MPMX19_02948 in Azospirillum sp. SherDot2

Annotation: Ribulose bisphosphate carboxylase large chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 transmembrane" amino acids 274 to 293 (20 residues), see Phobius details PF02788: RuBisCO_large_N" amino acids 38 to 158 (121 residues), 155.9 bits, see alignment E=5.2e-50 PF00016: RuBisCO_large" amino acids 168 to 475 (308 residues), 447.4 bits, see alignment E=2.3e-138

Best Hits

Swiss-Prot: 81% identical to RBL_RHOP5: Ribulose bisphosphate carboxylase large chain (cbbL) from Rhodopseudomonas palustris (strain BisA53)

KEGG orthology group: K01601, ribulose-bisphosphate carboxylase large chain [EC: 4.1.1.39] (inferred from 93% identity to rce:RC1_4061)

MetaCyc: 59% identical to CbbL (Synechocystis sp. PCC 6803)

Predicted SEED Role

"Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39)" in subsystem CO2 uptake, carboxysome or Calvin-Benson cycle or Carboxysome or Photorespiration (oxidative C2 cycle) (EC 4.1.1.39)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.39

Use Curated BLAST to search for 4.1.1.39

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (498 amino acids)

>MPMX19_02948 Ribulose bisphosphate carboxylase large chain (Azospirillum sp. SherDot2)
MNYVSTTLPPDQKAGDAVVSDPKARYRPGVLKYRQMGYWEPDYEPKDTDILAVFRITPQD
GVDPEEAAAAVAGESSTATWTVVWTDRLTDCERYRAKAFRVDPVPGMSGQYFAYIAYELD
LFEEGSIANLTASIIGNVFGFKPLKGLRLEDMRIPIAYLKTFQGPATGIVVERERLNNFG
RPLLGATMKPKLGLSGRNYGRVVYEALKGGLDFTKDDENINSQPFMHWRDRFLYCMEGVN
RATAETGEIKGTYLNVTAATMEDMYERAEFAKELGSVIVMIDLVIGYTAIQSMAKWARRN
DMILHLHRAGHSTYTRQKNHGVSFRVIAKWMRMAGVDHIHAGTVVGKLEGDPNVIRGIYD
TCRETHVPQNLQHGIFFDQSWAGLKRMMPVASGGIHAGQMHQLLTYLGEDVILQFGGGTI
GHPDGIQAGATANRVALETMVKARNEGRDIWNEGPEILREAARWCAPLRAALDTWKDVTF
DYASTDSVDYVPTPTPAM