Protein Info for MPMX19_02839 in Azospirillum sp. SherDot2

Annotation: Acetyl-S-ACP:malonate ACP transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 TIGR01110: malonate decarboxylase, alpha subunit" amino acids 4 to 551 (548 residues), 959.1 bits, see alignment E=3.2e-293 PF16957: Mal_decarbox_Al" amino acids 4 to 551 (548 residues), 984 bits, see alignment E=8.8e-301

Best Hits

Swiss-Prot: 67% identical to MADA_MALRU: Acetyl-S-ACP:malonate ACP transferase (madA) from Malonomonas rubra

KEGG orthology group: K13929, malonate decarboxylase alpha subunit [EC: 2.3.1.187] (inferred from 95% identity to azl:AZL_b03140)

MetaCyc: 67% identical to acetyl-[acyl-carrier protein]:malonate [acyl-carrier protein] transferase (Malonomonas rubra)
RXN-9774 [EC: 7.2.4.4]; Acetyl-S-ACP:malonate ACP transferase. [EC: 7.2.4.4, 2.3.1.187]

Predicted SEED Role

"Malonate decarboxylase alpha subunit" in subsystem Malonate decarboxylase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.187 or 7.2.4.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (551 amino acids)

>MPMX19_02839 Acetyl-S-ACP:malonate ACP transferase (Azospirillum sp. SherDot2)
MRDWNLQGRNRDARLARAASLVPSSTGGKRVATADARALLEAVLEPGDRVCLEGNNQKQA
DFLARTLASVDPARVNGLHMVQSVLALPEHLDVFERGIAAKLDFSFSGPQGARLARMVAD
GRISVGAIHTYLELFGRYFVDLTPRVSLVAAQAADAVGNLYTGPNTEDTPVIVEATAFKR
GIVIAQVNELVDSVPRVDIPGGWVDFVIQSPTPHYIEPLFTRDPAQISEIQVLMAMMAIK
GIYAEYGIQRLNHGIGFDTAAIELLLPTYAESLGLKGKICRHWALNPHPALIPAIEAGFV
ESVHSFGSELGMEAYIRARPDVFFTGADGNMRSNRAMSQAAGHYACDLFIGSTLQIDLAG
NSSTATLGRIAGFGGAPNMGADARGRRHASPAWLKAGREARGDGGQMPRGQKLVVQMVET
FREHMQPAFVERLDAWDLAESAGMELPPVMIYGDDVTHILTEEGIANLLLCRTAEEREQA
IRGVAGYTPVGRGRDRRMVENLRDRGVIRRPEDLGIDKRLATRDLLAARSVKDLVRASGG
LYDPPKRFRNW