Protein Info for MPMX19_02831 in Azospirillum sp. SherDot2

Annotation: Acetylpolyamine amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 PF00850: Hist_deacetyl" amino acids 27 to 341 (315 residues), 241.3 bits, see alignment E=7.4e-76

Best Hits

Swiss-Prot: 52% identical to APAHL_BURP1: Acetylpolyamine amidohydrolase (aphA) from Burkholderia pseudomallei (strain 1710b)

KEGG orthology group: None (inferred from 96% identity to azl:AZL_b03220)

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (354 amino acids)

>MPMX19_02831 Acetylpolyamine amidohydrolase (Azospirillum sp. SherDot2)
MKFVHHPDAALHRPATYFNKGLLRALPEKPERVGALASLIEKRGETLILPDDYGSAPRAA
VHTPAYLAFLETAHARWVATGDMGDVVLPNVHRMQAAPNYPTGIVGQAGWHMFDTACPIG
EGTWAATCAASNAAIHAAKLVATGADSAAYALCRPPGHHATRDMAGGFCYLNHVAVAAES
VLPLLRAQGRPARVAIIDVDVHHGNGTQDIFYERDDVFFVSVHGDPAEFYPHMAGYAQER
GIGRGEGYNLNLPLPIGSDEATVLATIGKGLDAIRRFAPEMLFVSLGFDTFIDDPLAAFG
VTTPGFARMGALLAATGLPTVLVQEGGYAIDDLSANLSSFLDGFQGGFEGKTAA