Protein Info for MPMX19_02746 in Azospirillum sp. SherDot2

Annotation: Peptidyl-lysine N-acetyltransferase Pat

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 903 PF02629: CoA_binding" amino acids 11 to 103 (93 residues), 31.9 bits, see alignment E=7.6e-11 PF13380: CoA_binding_2" amino acids 14 to 132 (119 residues), 73.1 bits, see alignment E=1e-23 PF13607: Succ_CoA_lig" amino acids 149 to 286 (138 residues), 184.6 bits, see alignment E=3.1e-58 PF19045: Ligase_CoA_2" amino acids 298 to 446 (149 residues), 28.5 bits, see alignment E=5.7e-10 PF13549: ATP-grasp_5" amino acids 487 to 708 (222 residues), 302.7 bits, see alignment E=5.6e-94 PF13302: Acetyltransf_3" amino acids 741 to 880 (140 residues), 33.1 bits, see alignment E=3.5e-11 PF00583: Acetyltransf_1" amino acids 806 to 879 (74 residues), 39.9 bits, see alignment E=1.9e-13

Best Hits

KEGG orthology group: K09181, hypothetical protein (inferred from 96% identity to azl:AZL_026900)

Predicted SEED Role

"Protein acetyltransferase" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (903 amino acids)

>MPMX19_02746 Peptidyl-lysine N-acetyltransferase Pat (Azospirillum sp. SherDot2)
MTVRNLDKLFKPASIALIGASRKPGTVGAVVARNLFQAGFDGPVMPVNPTERAVEGVLTY
KTVDSLPITPDLGVICTAPDTVAATIDALGKRGTKAAIVMTKGMSADQTQAMLDTAKPYL
MRVLGPNSLGAMVPGRGMNASFAPVAPRKGDVALVAQSSMVLTSVADWATSRGIGFSHLV
SLGDRGDVDFGDLLDYLASDVTVRAILLYIESITQARKFMSAARSASRQKPVIVIKAGRS
DEAQEAAASHTGALAVSDAVYDAVFRRAGVLRVNDLAELFDAAGTLGTGVPITGDRLAIL
TNGGGMGVMATDKLIQAGGRLAAMAPETQEALAKALGPQPGGGQPGGAPFRNPLRIGADA
TPKRYAEALNALMQDTGNDAVLVLHCPSALTDSEAIAQAVAETVQANKARRHPVLTSWIG
DQSAVEARKLFADGRIPTYSGPSDAVRAFMHLVRYRRSQQLLMETPPSVAEDFQPDEITV
KKVISRAMAEKREWLSEYEAKRVLAAYGIPVVDTRVAQTPEEAAAAARVIGGPIALKILS
HDITHKSDVGGVALGLTSPEDVKAEAEAMLARVAELAPEAKIEGFTVQEMAVRPDAYELI
VGMTENEMFGPVLLFGEGGIGVEVVEDYALALPPLNMKLAAEQMSRTRIHRQLQGYRSRA
AVDLDAVALTLNKVSQLVVDFPEIAEMDINPLLADAEGVTALDARIKVGVPALAGAARLA
IRPYPKSLEDRITIKDGRQFFVRPILPEDEPLVHHLVENQTAEDLRLRFFAPLKRLSHQA
AARLTQIDYDREMGLIAVGPDPQTGDTIMYGVVRITADPDNRRAEYAVMVRSDMKGQGLG
YIMMNKILDYARSRGIKEVYGEVLRENTNMLNMCRALGFVRKENLDEPGVVEVRIELGGG
LAA